Minocycline has anti-inflammatory, antioxidant, and anti-apoptotic properties that explain the
renewed interest in its use as an adjunctive treatment for psychiatric and neurological …

Minocycline is a widely used glial activation inhibitor that could suppress pain-related
behaviors in a number of different pain animal models, yet, its analgesic mechanisms are …

Substantial evidence indicates involvement of microglia/macrophages in chronic
neuropathic pain. However, the temporal-spatial features of microglial/macrophage …

For a long time, minocycline has been recognized as highly efficacious for the treatment of
acne vulgaris but with use-limiting acute vestibular adverse events (AVAEs). Based on the …

It has been well established that neurogenic inflammation is one of the major pathological
processes underlying inflammatory pain, but there are few effective anti‐inflammatory drugs …

The mechanisms associated with diabetes‑induced neuropathic pain are complex and
poorly understood. In order to understand the involvement of spinal microglia activity in …

Purpose Minocycline is a microglial cell inhibitor and decreases pain behaviors in animal
models. Minocycline might represent an intervention for reducing postoperative pain. This …

Glutamate homeostasis and microglia activation play an important role in the development
and maintenance of neuropathic pain. So far, there has been insufficient data on the …

BACKGROUND: Pain and depression are highly prevalent symptoms in cancer patients.
They tend to occur simultaneously and affect each other and share biological pathways and …

Experimental autoimmune neuritis (EAN) is a widely used animal model of the human acute
inflammatory demyelinating polyradiculoneuropathy, which is the most common subtype of …