[HTML][HTML] Analgesic effect of a single preoperative dose of the antibiotic ceftriaxone in humans
A Macaluso, M Bernabucci, A Trabucco, L Ciolli… - The Journal of …, 2013 - Elsevier
Repeated injections of the antibiotic ceftriaxone cause analgesia in rodents by upregulating
the glutamate transporter, GLT-1. No evidence is available in humans. We studied the effect …
the glutamate transporter, GLT-1. No evidence is available in humans. We studied the effect …
The potential of traditional Chinese medicine in the treatment and modulation of pain
G Du, T Yuan, Y Zhang - Advances in pharmacology, 2016 - Elsevier
Pain is an unpleasant sensory and emotional experience associated with various diseases.
Extensive research has been conducted to find appropriate methods of relieving pain and …
Extensive research has been conducted to find appropriate methods of relieving pain and …
[HTML][HTML] Intrathecal rapamycin attenuates morphine-induced analgesic tolerance and hyperalgesia in rats with neuropathic pain
Repeated and long-term administration of opioids is often accompanied by the initiation of
opioid-induced analgesic tolerance and hyperalgesia in chronic pain patients. Our previous …
opioid-induced analgesic tolerance and hyperalgesia in chronic pain patients. Our previous …
L Type Ca2+ Channel Blockers Prevent Oxaliplatin-Induced Cold Hyperalgesia and TRPM8 Overexpression in Rats
T Kawashiri, N Egashira, K Kurobe… - Molecular …, 2012 - journals.sagepub.com
Background: Oxaliplatin is an important drug used in the treatment of colorectal cancer.
However, it frequently causes severe acute and chronic peripheral neuropathies. We …
However, it frequently causes severe acute and chronic peripheral neuropathies. We …
Repeated administration of amitriptyline reduces oxaliplatin-induced mechanical allodynia in rats
H Sada, N Egashira, S Ushio, T Kawashiri… - Journal of …, 2012 - Elsevier
Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes acute and chronic
neuropathies in patients. Amitriptyline has widely been used in patients with painful …
neuropathies in patients. Amitriptyline has widely been used in patients with painful …
[HTML][HTML] Diosmetin alleviates neuropathic pain by regulating the Keap1/Nrf2/NF-κB signaling pathway
L Zhao, X Tao, Q Wang, X Yu, D Dong - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Background Neuropathic pain, a chronic condition with a high incidence, imposes
psychological burdens on both patients and society. It is urgent to improve pain …
psychological burdens on both patients and society. It is urgent to improve pain …
[HTML][HTML] Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms
PSA Augusto, AV Braga, FF Rodrigues… - European Journal of …, 2019 - Elsevier
Metformin, an AMP-activated protein kinase (AMPK) activator, is an oral hypoglycemic drug
widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive …
widely used to treat patients with type 2 diabetes. As AMPK plays a role in the nociceptive …
Pharmacological regulation of neuropathic pain driven by inflammatory macrophages
N Kiguchi, D Kobayashi, F Saika, S Matsuzaki… - International journal of …, 2017 - mdpi.com
Neuropathic pain can have a major effect on quality of life but current therapies are often
inadequate. Growing evidence suggests that neuropathic pain induced by nerve damage is …
inadequate. Growing evidence suggests that neuropathic pain induced by nerve damage is …
Ethosuximide reverses paclitaxel-and vincristine-induced painful peripheral neuropathy
SJL Flatters, GJ Bennett - Pain, 2004 - Elsevier
Paclitaxel (Taxol®) is one of the most effective and frequently used chemotherapeutics for
the treatment of solid tumours. However, paclitaxel produces peripheral neurotoxicity with …
the treatment of solid tumours. However, paclitaxel produces peripheral neurotoxicity with …
Minocycline: therapeutic potential in psychiatry
OM Dean, J Data-Franco, F Giorlando, M Berk - CNS drugs, 2012 - Springer
Pharmacological interventions to treat psychiatric illness have previously focused on
modifying dysfunctional neurotransmitter systems to improve symptoms. However, imperfect …
modifying dysfunctional neurotransmitter systems to improve symptoms. However, imperfect …