Prenatal infection, maternal immune activation, and risk for schizophrenia

SE Canetta, AS Brown - Translational neuroscience, 2012 - Springer
A body of epidemiological literature has suggested an association between prenatal
infection, subsequent maternal immune activation (MIA), and later risk of schizophrenia …

Prenatal and postnatal maternal contributions in the infection model of schizophrenia

U Meyer, S Schwendener, J Feldon, BK Yee - Experimental brain research, 2006 - Springer
Epidemiological studies have indicated that the risk of schizophrenia is enhanced by
prenatal maternal infection with viral or bacterial pathogens. Recent experimentation in …

A review of the fetal brain cytokine imbalance hypothesis of schizophrenia

U Meyer, J Feldon, BK Yee - Schizophrenia bulletin, 2009 - academic.oup.com
Maternal infection during pregnancy increases the risk of schizophrenia and other brain
disorders of neurodevelopmental origin in the offspring. A multitude of infectious agents …

Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin …

C Winter, A Djodari-Irani, R Sohr… - International Journal …, 2009 - academic.oup.com
Maternal infection during pregnancy enhances the offspring's risk for severe
neuropsychiatric disorders in later life, including schizophrenia. Recent attempts to model …

Neural basis of psychosis-related behaviour in the infection model of schizophrenia

U Meyer, J Feldon - Behavioural brain research, 2009 - Elsevier
Maternal infection during pregnancy is a notable risk factor for the offspring to develop
severe neuropsychiatric disorders, including schizophrenia. One prevalent hypothesis …

Effects of prenatal infection on brain development and behavior: a review of findings from animal models

P Boksa - Brain, behavior, and immunity, 2010 - Elsevier
Epidemiological studies with human populations indicate associations between maternal
infection during pregnancy and increased risk in offspring for central nervous system (CNS) …

Prenatal maternal infection, neurodevelopment and adult schizophrenia: a systematic review of population-based studies

GM Khandaker, J Zimbron, G Lewis… - Psychological …, 2013 - cambridge.org
BackgroundDisruption of foetal development by prenatal maternal infection is consistent
with a neurodevelopmental model of schizophrenia. Whether specific prenatal infections are …

Prenatal infection and schizophrenia: a review of epidemiologic and translational studies

AS Brown, EJ Derkits - American Journal of Psychiatry, 2010 - Am Psychiatric Assoc
An emerging literature from epidemiologic, clinical, and preclinical investigations has
provided evidence that gestational exposure to infection contributes to the etiology of …

Maternal immune activation and schizophrenia–evidence for an immune priming disorder

Z Choudhury, B Lennox - Frontiers in Psychiatry, 2021 - frontiersin.org
Schizophrenia is a complex neurodevelopmental disorder affecting around 19. 8 million
people worldwide. The etiology of the disorder is due to many interacting genetic and …

Maternal immune activation and autism spectrum disorder: from rodents to nonhuman and human primates

M Careaga, T Murai, MD Bauman - Biological psychiatry, 2017 - Elsevier
A subset of women who are exposed to infection during pregnancy have an increased risk of
giving birth to a child who will later be diagnosed with a neurodevelopmental or …