Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation
R Hadar, L Dong, L del-Valle-Anton… - Brain, Behavior, and …, 2017 - Elsevier
In recent years schizophrenia has been recognized as a neurodevelopmental disorder likely
involving a perinatal insult progressively affecting brain development. The poly I: C maternal …
involving a perinatal insult progressively affecting brain development. The poly I: C maternal …
Prenatal exposure to infection: a primary mechanism for abnormal dopaminergic development in schizophrenia
Rationale Prenatal exposure to infection is a notable environmental risk factor in the
development of schizophrenia. One prevalent hypothesis suggests that infection-induced …
development of schizophrenia. One prevalent hypothesis suggests that infection-induced …
Prenatal poly (i: C) exposure and other developmental immune activation models in rodent systems
U Meyer - Biological psychiatry, 2014 - Elsevier
It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …
development of schizophrenia and related psychotic illnesses. On the basis of human …
[HTML][HTML] Maternal immune activation causes behavioral impairments and altered cerebellar cytokine and synaptic protein expression
G Pendyala, S Chou, Y Jung, P Coiro… - …, 2017 - nature.com
Emerging epidemiology studies indicate that maternal immune activation (MIA) resulting
from inflammatory stimuli such as viral or bacterial infections during pregnancy serves as a …
from inflammatory stimuli such as viral or bacterial infections during pregnancy serves as a …
Neonatal behavioral changes in rats with gestational exposure to lipopolysaccharide: a prenatal infection model for developmental neuropsychiatric disorders
M Baharnoori, SK Bhardwaj… - Schizophrenia …, 2012 - academic.oup.com
Exposure to prenatal infections has been widely associated with the increased risk for
neuropsychiatric disorders of developmental origin such as schizophrenia and autism …
neuropsychiatric disorders of developmental origin such as schizophrenia and autism …
Epigenetic changes at gene promoters in response to immune activation in utero
Increasing evidence suggests that maternal infection increases the risk of psychiatric
disorders, such as schizophrenia and autism in offspring. However, the molecular …
disorders, such as schizophrenia and autism in offspring. However, the molecular …
The role of HLA-G in cytokine homeostasis during early pregnancy complicated with maternal infections: a novel etiopathological approach to the neurodevelopmental …
M Debnath, TK Chaudhuri - Medical hypotheses, 2006 - Elsevier
Schizophrenia is perhaps the most enigmatic and tragic psychotic disorder with remarkable
mortality and morbidity. Schizophrenia is complex and clinically a heterogeneous disorder …
mortality and morbidity. Schizophrenia is complex and clinically a heterogeneous disorder …
Maternal influenza infection during pregnancy impacts postnatal brain development in the rhesus monkey
SJ Short, GR Lubach, AI Karasin, CW Olsen… - Biological …, 2010 - Elsevier
BACKGROUND: Maternal infection with influenza and other pathogens during pregnancy
has been associated with increased risk for schizophrenia and neurodevelopmental …
has been associated with increased risk for schizophrenia and neurodevelopmental …
Maternal immune activation alters glutamic acid decarboxylase-67 expression in the brains of adult rat offspring
SN Cassella, AM Hemmerle, KH Lundgren… - Schizophrenia …, 2016 - Elsevier
Activation of the maternal innate immune system, termed “maternal immune activation”(MIA),
represents a common environmental risk factor for schizophrenia. Whereas evidence …
represents a common environmental risk factor for schizophrenia. Whereas evidence …
Maternal infection and the offspring brain
AM Depino - Journal of neuroscience, 2006 - Soc Neuroscience
Infections are a common complication of pregnancy that can lead to miscarriage and
stillbirth. Epidemiological studies have associated infections caused by virus and bacteria …
stillbirth. Epidemiological studies have associated infections caused by virus and bacteria …