Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation

R Hadar, L Dong, L del-Valle-Anton… - Brain, Behavior, and …, 2017 - Elsevier
In recent years schizophrenia has been recognized as a neurodevelopmental disorder likely
involving a perinatal insult progressively affecting brain development. The poly I: C maternal …

Prenatal exposure to infection: a primary mechanism for abnormal dopaminergic development in schizophrenia

U Meyer, J Feldon - Psychopharmacology, 2009 - Springer
Rationale Prenatal exposure to infection is a notable environmental risk factor in the
development of schizophrenia. One prevalent hypothesis suggests that infection-induced …

Prenatal poly (i: C) exposure and other developmental immune activation models in rodent systems

U Meyer - Biological psychiatry, 2014 - Elsevier
It is increasingly appreciated that altered neuroimmune mechanisms might play a role in the
development of schizophrenia and related psychotic illnesses. On the basis of human …

[HTML][HTML] Maternal immune activation causes behavioral impairments and altered cerebellar cytokine and synaptic protein expression

G Pendyala, S Chou, Y Jung, P Coiro… - …, 2017 - nature.com
Emerging epidemiology studies indicate that maternal immune activation (MIA) resulting
from inflammatory stimuli such as viral or bacterial infections during pregnancy serves as a …

Neonatal behavioral changes in rats with gestational exposure to lipopolysaccharide: a prenatal infection model for developmental neuropsychiatric disorders

M Baharnoori, SK Bhardwaj… - Schizophrenia …, 2012 - academic.oup.com
Exposure to prenatal infections has been widely associated with the increased risk for
neuropsychiatric disorders of developmental origin such as schizophrenia and autism …

Epigenetic changes at gene promoters in response to immune activation in utero

B Tang, H Jia, RJ Kast, EA Thomas - Brain, behavior, and immunity, 2013 - Elsevier
Increasing evidence suggests that maternal infection increases the risk of psychiatric
disorders, such as schizophrenia and autism in offspring. However, the molecular …

The role of HLA-G in cytokine homeostasis during early pregnancy complicated with maternal infections: a novel etiopathological approach to the neurodevelopmental …

M Debnath, TK Chaudhuri - Medical hypotheses, 2006 - Elsevier
Schizophrenia is perhaps the most enigmatic and tragic psychotic disorder with remarkable
mortality and morbidity. Schizophrenia is complex and clinically a heterogeneous disorder …

Maternal influenza infection during pregnancy impacts postnatal brain development in the rhesus monkey

SJ Short, GR Lubach, AI Karasin, CW Olsen… - Biological …, 2010 - Elsevier
BACKGROUND: Maternal infection with influenza and other pathogens during pregnancy
has been associated with increased risk for schizophrenia and neurodevelopmental …

Maternal immune activation alters glutamic acid decarboxylase-67 expression in the brains of adult rat offspring

SN Cassella, AM Hemmerle, KH Lundgren… - Schizophrenia …, 2016 - Elsevier
Activation of the maternal innate immune system, termed “maternal immune activation”(MIA),
represents a common environmental risk factor for schizophrenia. Whereas evidence …

Maternal infection and the offspring brain

AM Depino - Journal of neuroscience, 2006 - Soc Neuroscience
Infections are a common complication of pregnancy that can lead to miscarriage and
stillbirth. Epidemiological studies have associated infections caused by virus and bacteria …