We developed a mouse model of Staphylococcus aureus infective endocarditis to evaluate
the efficacy of experimental antibacterial compounds for this disease. Experimental infective …

Endovascular infections, including endocarditis, are life-threatening infectious syndromes1-
3. Staphylococcus aureus is the most common world-wide cause of such syndromes with …

Animal models are commonly used to determine the efficacy of various antimicrobial agents
for treatment of bacterial endocarditis. Previously we have utilized an in vitro infection model …

We present a new experimental model of Staphylococcus aureus infective endocarditis in
guinea pigs. Permanent aortic valve damage was produced by electrocoagulation after …

We compared the efficacy of ciprofloxacin with that of vancomycin by using the rabbit model
of methicillin-resistant Staphylococcus aureus endocarditis. Endocarditis was treated with …

Bacterial endocarditis is a difficult-to-curc infection, owing to (i) poor penetration of
antibiotics into infected vegetations;(ii) altered metabolic state of bacteria within the …

Background. Recurrent therapeutic failures reported for the treatment of methicillin-resistant
Staphylococcus aureus (MRSA) infective endocarditis (IE) with vancomycin may be due to …

Comparison of Antimicrobial Agents as Therapy for Experimental Endocarditis Caused by
Methicillin-Resistant Staphylococcus aureus - PMC Back to Top Skip to main content NIH NLM …

The empiric treatment of infective endocarditis (IE) varies widely and, in some places, a
regimen of penicillin in combination with an aminoglycoside is administered. The increasing …

The in vivo efficacy of daptomycin, a new cell wall-active anti-gram-positive-bacterial agent,
was compared to those of cloxacillin and vancomycin in a rat model of Staphylococcus …