Helminth modulation of lung inflammation

C Schwartz, E Hams, PG Fallon - Trends in parasitology, 2018 - cell.com
Parasitic helminths must establish chronic infections to complete their life cycle and
therefore are potent modulators of multiple facets of host physiology. Parasitic helminths …

Host immunity and inflammation to pulmonary helminth infections

JE Weatherhead, P Gazzinelli-Guimaraes… - Frontiers in …, 2020 - frontiersin.org
Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms
that infect at least one billion people globally living in extreme poverty. Helminthic infections …

Helminths in the lungs

JM Craig, AL Scott - Parasite immunology, 2014 - Wiley Online Library
Parasitic helminths infect well over one billion people and typically cause chronic and
recurrent infections that exert a considerable toll on human health and productivity. A …

What can parasites tell us about the pathogenesis and treatment of asthma and allergic diseases

S Bohnacker, F Troisi, M de los Reyes Jiménez… - Frontiers in …, 2020 - frontiersin.org
The same mechanisms that enable host defense against helminths also drive allergic
inflammation. This suggests that pathomechanisms of allergic diseases represent …

[HTML][HTML] Parasitic helminth infections and the control of human allergic and autoimmune disorders

RM Maizels - Clinical Microbiology and Infection, 2016 - Elsevier
The profile of global health today presents a striking reciprocal distribution between parasitic
diseases in many of the world's lower-income countries, and ever-increasing levels of …

Chronic helminth infections modulate allergen‐specific immune responses: protection against development of allergic disorders?

HH Smits, M Yazdanbakhsh - Annals of medicine, 2007 - Taylor & Francis
Inflammatory diseases are on the rise in westernized countries, but also in urbanized areas
of developing countries. A number of studies have now demonstrated a negative association …

Regulation of type 1 diabetes, tuberculosis, and asthma by parasites

Z Liu, Q Liu, D Bleich, P Salgame… - Journal of molecular …, 2010 - Springer
Helminth infection is a worldwide health problem. In addition to directly causing disease,
helminthic infection also affects the incidence and progression of other diseases by exerting …

Enteric helminth-induced type I interferon signaling protects against pulmonary virus infection through interaction with the microbiota

AJ McFarlane, HJ McSorley, DJ Davidson… - Journal of Allergy and …, 2017 - Elsevier
Background Helminth parasites have been reported to have beneficial immunomodulatory
effects in patients with allergic and autoimmune conditions and detrimental consequences in …

Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness

NE Mangan, N van Rooijen, ANJ McKenzie… - The Journal of …, 2006 - journals.aai.org
It has been shown that the presence of certain helminth infections in humans, including
schistosomes, may reduce the propensity to develop allergies in infected populations. Using …

[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …