Polycythemia vera disease burden: contributing factors, impact on quality of life, and emerging treatment options

BL Stein, AR Moliterno, RV Tiu - Annals of hematology, 2014 - Springer
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm characterized by clonal
expansion of a hematopoietic progenitor, erythrocytosis, often leukocytosis and/or …

Current and future treatment options for polycythemia vera

M Griesshammer, H Gisslinger, R Mesa - Annals of hematology, 2015 - Springer
Patients with polycythemia vera (PV), a myeloproliferative neoplasm characterized by an
elevated red blood cell mass, are at high risk of vascular and thrombotic complications and …

Diagnosis and management of cardiovascular risk in patients with polycythemia vera

G Benevolo, M Marchetti, R Melchio… - Vascular Health and …, 2023 - Taylor & Francis
Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by aberrant myeloid
lineage hematopoiesis with excessive red blood cell and pro-inflammatory cytokine …

Polycythemia vera: from new, modified diagnostic criteria to new therapeutic approaches

M Maffioli, B Mora, F Passamonti - Clinical Advances in Hematology & …, 2017 - air.unimi.it
Polycythemia vera (PV) is a Philadelphia chromosomeâ negative chronic myeloproliferative
neoplasm that is associated with a Janus kinase 2 (JAK2) mutation in most cases. The most …

Treatment and clinical endpoints in polycythemia vera: seeking the best obtainable version of the truth

J Gotlib - Blood, The Journal of the American Society of …, 2022 - ashpublications.org
Polycythemia vera (PV) is a Philadelphia chromosome-negative myeloproliferative
neoplasm driven by the JAK2 V617F (or rarely exon 12) mutation. Its natural history can …

[HTML][HTML] Polycythemia vera: thinking beyond the hematocrit

M Waggoner - Journal of the Advanced Practitioner in Oncology, 2023 - ncbi.nlm.nih.gov
Polycythemia vera is a Philadelphia chromosome–negative myeloproliferative neoplasm
that results in increased myeloproliferation. It is a debilitating disease characterized by the …

Polycythemia vera: rapid evidence review

S Fox, L Griffin, DR Harris - American family physician, 2021 - aafp.org
Polycythemia vera is one of three stem-cell–derived myeloid malignancies commonly known
as myeloproliferative neoplasms. It is characterized by erythrocytosis, often with associated …

Polycythemia vera: 2024 update on diagnosis, risk‐stratification, and management

A Tefferi, T Barbui - American journal of hematology, 2023 - Wiley Online Library
Abstract Disease Overview Polycythemia vera (PV) is a JAK2‐mutated myeloproliferative
neoplasm characterized by clonal erythrocytosis; other features include leukocytosis …

How we identify and manage patients with inadequately controlled polycythemia vera

A Reiter, C Harrison - Current hematologic malignancy reports, 2016 - Springer
Polycythemia vera (PV) is a chronic myeloproliferative neoplasm (MPN) characterized by an
overactive Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway …

Polycythemia vera management and challenges in the community health setting

AT Gerds, KH Dao - Oncology, 2017 - karger.com
Patients with polycythemia vera (PV) experience shortened survival, increased risk of
thromboembolic and hemorrhagic events, and burdensome symptoms. For all patients with …