Diet-derived polyphenols inhibit angiogenesis by modulating the interleukin-6/STAT3 pathway

S Lamy, N Akla, A Ouanouki, S Lord-Dufour… - Experimental cell …, 2012 - Elsevier
Several epidemiological studies have indicated that abundant consumption of foods from
plant origin is associated with a reduced risk of developing several types of cancers. This …

Polyphenol-based nutraceuticals for the control of angiogenesis: Analysis of the critical issues for human use

L Morbidelli - Pharmacological Research, 2016 - Elsevier
Angiogenesis, the formation of new blood-vessel, is crucial in the pathogenesis of several
diseases, and thus represents a druggable target for the prevention and treatment of …

The antiangiogenic activity of polyphenol-rich extracts and its implication on cancer chemoprevention

K Chojnacka, U Lewandowska - Food Reviews International, 2020 - Taylor & Francis
Plant-based diet has many valuable properties, and natural polyphenols that are contained
in fruits, vegetables or beverages have numerous beneficial functions. They are well-known …

Antiangiogenic mechanisms of diet-derived polyphenols

Y Cao, R Cao, E Bråkenhielm - The Journal of Nutritional Biochemistry, 2002 - Elsevier
Accumulating evidence demonstrates that polyphenols in natural products are beneficial
against human lethal diseases such as cancer and metastasis. The underlying mechanisms …

Mediterranean diet polyphenols reduce inflammatory angiogenesis through MMP-9 and COX-2 inhibition in human vascular endothelial cells: a potentially protective …

E Scoditti, N Calabriso, M Massaro, M Pellegrino… - Archives of biochemistry …, 2012 - Elsevier
Diets with high content of antioxidant polyphenols are associated with low prevalence of
cardiovascular diseases and cancer. Inflammatory angiogenesis is a key pathogenic …

Tumor angiogenesis–a potential target in cancer chemoprevention

TA Bhat, RP Singh - Food and chemical toxicology, 2008 - Elsevier
Tumor angiogenesis is critically important for the growth of solid tumors as tumors remain in
dormant phase for a long time in the absence of the initiation of blood vessel formation …

Regulation of cell signaling pathways by dietary agents for cancer prevention and treatment

MK Pandey, SC Gupta, A Nabavizadeh… - Seminars in cancer …, 2017 - Elsevier
Although it is widely accepted that better food habits do play important role in cancer
prevention and treatment, how dietary agents mediate their effects remains poorly …

Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer

SC Reuben, A Gopalan, DM Petit… - Molecular nutrition & …, 2012 - Wiley Online Library
Breast cancer is the leading cause of cancer‐related deaths for women in the United States
and the rest of the world. About 8% of women develop breast cancer during the course of …

Cancer chemoprevention and chemotherapy: dietary polyphenols and signalling pathways

S Ramos - Molecular nutrition & food research, 2008 - Wiley Online Library
Prevention of cancer through dietary intervention recently has received an increasing
interest, and dietary polyphenols have become not only important potential …

Antiangiogenic phytochemicals constituent of diet as promising candidates for chemoprevention of cancer

AD Marrero, AR Quesada, B Martínez-Poveda… - Antioxidants, 2022 - mdpi.com
Despite the extensive knowledge on cancer nature acquired over the last years, the high
incidence of this disease evidences a need for new approaches that complement the clinical …