Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and proliferation by targeting phosphatidylinositol 3 …

E Bagli, M Stefaniotou, L Morbidelli, M Ziche, K Psillas… - Cancer research, 2004 - AACR
In an attempt to identify phytochemicals contributing to the well-documented preventive
effect of plant-based diets on cancer incidence and mortality, we have previously shown that …

New insights on the anticancer properties of dietary polyphenols

P Fresco, F Borges, C Diniz… - Medicinal research …, 2006 - Wiley Online Library
Cancer, one of the major causes of death across the world, has shown to be a largely
preventable disease, highly susceptible to modulation by dietary factors. Phenolic …

[PDF][PDF] Polyphenols, intracellular signalling and inflammation

C Santangelo, R Vari, B Scazzocchio… - … -istituto superiore di …, 2007 - researchgate.net
excessive inflammation is considered as a critical factor in many human diseases, including
cancer, obesity, type II diabetes, cardiovascular diseases, neurodegenerative diseases and …

Mechanistic study of the in vitro and in vivo inhibitory effects of protocatechuic acid and syringic acid on VEGF-induced angiogenesis

J Hu, S Lin, JJ Huang, PCK Cheung - Journal of agricultural and …, 2018 - ACS Publications
The antiangiogenic activities of two structurally similar phenolics, protocatechuic acid (PA)
and syringic acid (SA), were investigated. In vitro study using HUVECs demonstrated that …

Anti-angiogenesis efficacy of the garlic ingredient alliin and antioxidants: role of nitric oxide and p53

AS Mousa, SA Mousa - Nutrition and cancer, 2005 - Taylor & Francis
Alliin, a compound derived from garlic, demonstrated dose-dependent inhibition of fibroblast
growth factor-2 (FGF2)-induced human endothelial cell (EC) tube formation and …

Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis

T Fotsis, M Pepper, H Adlercreutz, T Hase… - The Journal of …, 1995 - Elsevier
Consumption of a plant-based diet can prevent the development and progression of chronic
diseases that are associated with extensive neovascularization. To determine whether …

Targeting signal transducers and activators of transcription (STAT) in human cancer by dietary polyphenolic antioxidants

H Amani, M Ajami, SN Maleki, H Pazoki-Toroudi… - Biochimie, 2017 - Elsevier
Over the course of the last three decades, a large body of evidence has shown that
polyphenols, the secondary metabolites occurring in plant foods and beverages, exert …

Modulation of inflammatory genes by natural dietary bioactive compounds

MH Pan, CS Lai, S Dushenkov… - Journal of agricultural and …, 2009 - ACS Publications
Several epidemiologic studies have shown that chronic inflammation predisposes
individuals to various types of cancer. Many cancers arise from sites of infection, chronic …

Effect of phenolic compounds on human health

This book, based on a Special Issue of Nutrients, contains a total of 12 papers (8 original
research and 4 reviews) on the effect of phenolic compounds on human health. The …

Piperine, a dietary phytochemical, inhibits angiogenesis

CD Doucette, AL Hilchie, R Liwski… - The Journal of nutritional …, 2013 - Elsevier
Angiogenesis plays an important role in tumor progression. Piperine, a major alkaloid
constituent of black pepper, has diverse physiological actions including killing of cancer …