Polyphenols are a large family of natural compounds widely distributed in plants and are the
most studied chemopreventive agents. The biological activities and mechanism (s) of …

Flavonoids have been proposed to act as chemopreventive agents in numerous
epidemiological studies and have been shown to inhibit angiogenesis and proliferation of …

Oxidative stress and associated mechanisms involving inflammation, aberrant signaling
pathways and gap junction intercellular communication is increasingly associated with the …

We investigated the anti-proliferative effects of an olive oil polyphenolic extract on human
colon adenocarcinoma cells. Analysis indicated that the extract contained hydroxytyrosol …

Globally, the second most common mortality reason is cancer. There are two types of risk
factors for cancer: intrinsic (unmodifiable) and non-intrinsic (modifiable). Bad lifestyle …

Nobiletin is a citrus polymethoxyflavonoid that suppresses tumor growth and metastasis,
both of which depend on angiogenesis. We recently identified nobiletin as a cell …

Polyphenols have tumoricidal effects via anti-proliferative, anti-angiogenic and cytotoxic
mechanisms and have recently been demonstrated to modulate the immune response …

Emerging evidence indicates that chronic inflammation and oxidative stress cluster together
with angiogenic imbalance in a wide range of pathologies. In general, natural polyphenols …

Dietary agents identified from fruits and vegetables contribute to keeping balanced cell
proliferation and preventing cell carcinogenesis. Dietary flavonoids, combined with other …

A cancer protective effect from plant-derived foods has been found with uncommon
consistency in epidemiologic studies. However, it has been difficult to identify specific …