In experimental liver fibrosis, activated hepatic stellate cells (HSCs) play a central role and
thus, induction of apoptosis of activated HSCs is a promising therapeutic strategy for liver …

Liver diseases such as hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma are one of
the major health challenges in the world and many conditions such as inadequate nutrition …

Morin exerts inhibitory effects on hepatic stellate cell (HSC) stimulation which is considered
important step for fibrogenesis in liver. These morin-induced inhibitory effects are mediated …

Abstract Background and Aim Liver fibrosis is associated with the deposition of the
extracellular matrix, and hepatic stellate cells (HSC s) are the major source of these matrix …

Few studies reported the antifibrotic effects of gallic acid (GA) despite its known
hepatoprotective and antioxidant activities. Accordingly, this study investigated the …

In this study, we were aimed to evaluate the probable effect of the crud extract of Silybum
marianum, with high polyphenolic content, on experimental nonalcoholic steatohepatitis …

In this study, the protective effect of extract of Hsian-tsao (Mesona procumbens)(EHT)
against liver fibrogenesis in carbon tetrachloride (CCl4)-injured rats was evaluated. The …

Activation of hepatic stellate cells (HSCs) plays a critical role in liver fibrosis. Scoparone, a
major constituent isolated from Artemisia capillaris, was reported to possess …

Hepatic fibrosis is a widespread alteration in the liver that primarily consists of increased
collagen deposition in the tissue. The aim of the present study was to evaluate the protective …

Background: Liver fibrosis is characterized by irreversible damage to liver parenchyma. The
mechanism of fibrosis is through activation of nuclear factor-kappa (NF-kβ), collagen …