Physical activity (PA) may modify the genetic effects that give rise to increased risk of
obesity. To identify adiposity loci whose effects are modified by PA, we performed genome …

Numerous obesity loci have been identified using genome-wide association studies. A UK
study indicated that physical activity may attenuate the cumulative effect of 12 of these loci …

Physical activity (PA) has been shown to reduce the impact of FTO variation and obesity
genetic risk scores (GRS) on BMI. We examined this interaction using a quantitative …

To identify genetic loci influencing central obesity and fat distribution, we performed a meta-
analysis of 16 genome-wide association studies (GWAS, N= 38,580) informative for adult …

This review of the exercise genomics literature emphasizes the highest quality papers
published in 2011. Given this emphasis on the best publications, only a small number of …

Genome-wide discovery efforts have identified more than 500 genetic loci associated with
adiposity traits. The vast majority of these loci were found through large-scale meta-analyses …

Obesity is a worldwide health problem that is closely linked to many metabolic disorders.
Regular physical exercise has been found to attenuate the genetic predisposition to obesity …

Evidence that physical activity (PA) modulates the association between the fat mass and
obesity-associated gene (FTO) and BMI is emerging; however, information about dietary …

Objective To examine whether the effect of FTO loci on obesity‐related traits could be
modified by physical activity (PA) levels in European adults. Methods Of 1,607 Food4Me …

Background We have previously shown that multiple genetic loci identified by genome-wide
association studies (GWAS) increase the susceptibility to obesity in a cumulative manner. It …