Fcγ receptor–mediated induction of dendritic cell maturation and major histocompatibility complex class I–restricted antigen presentation after immune complex …

A Regnault, D Lankar, V Lacabanne… - The Journal of …, 1999 - rupress.org
Dendritic cells (DCs) express several receptors for the Fc portion of immunoglobulin (Ig) G
(FcγR), which mediate internalization of antigen–IgG complexes (immune complexes, ICs) …

Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8CD11b+ dendritic cells

K Baker, SW Qiao, TT Kuo… - Proceedings of the …, 2011 - National Acad Sciences
Cross-presentation of IgG-containing immune complexes (ICs) is an important means by
which dendritic cells (DCs) activate CD8+ T cells, yet it proceeds by an incompletely …

Control of cross‐presentation during dendritic cell maturation

BC Gil‐Torregrosa… - European journal of …, 2004 - Wiley Online Library
The initiation of most cytotoxic immune responses requires MHC class I‐restricted
presentation of internalized antigens to CD8+ T lymphocytes, a process called cross …

Presentation of exogenous antigens on major histocompatibility complex (MHC) class I and MHC class II molecules is differentially regulated during dendritic cell …

L Delamarre, H Holcombe, I Mellman - The Journal of experimental …, 2003 - rupress.org
During maturation, dendritic cells (DCs) regulate their capacity to process and present major
histocompatibility complex (MHC) II–restricted antigens. Here we show that presentation of …

Fcε receptor I on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC class II presentation

D Maurer, E Fiebiger, B Reininger, C Ebner… - The Journal of …, 1998 - journals.aai.org
In this study, we elucidate the FcεRI-mediated Ag uptake and presentation mechanisms of
dendritic cells (DC). We found that FcεRI-bound IgE, after polyvalent but not after …

Regulation of MHC class I transport in human dendritic cells and the dendritic-like cell line KG-1

AL Ackerman, P Cresswell - The Journal of Immunology, 2003 - journals.aai.org
Dendritic cells (DCs) progress through distinct maturational phases; immature DCs capture
Ag while mature DCs are optimized for Ag presentation. Proper control of immunity requires …

Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo

DH Schuurhuis, A Ioan-Facsinay… - The Journal of …, 2002 - journals.aai.org
Dendritic cells (DCs) require a maturation signal to acquire efficient CTL-priming capacity. In
vitro FcγR-mediated internalization of Ag-Ab immune complexes (ICs) can induce …

Accelerated antigen presentation and elicitation of humoral response in vivo by FcγRIIB-and FcγRI/III-mediated immune complex uptake

A Yada, S Ebihara, K Matsumura, S Endo, T Maeda… - Cellular …, 2003 - Elsevier
It is well established that activating-type Fc receptors for IgG (FcγR), such as FcγRI and
FcγRIII, are essential for inducing inflammatory responses, whereas a unique inhibitory …

The function of Fcγ receptors in dendritic cells and macrophages

M Guilliams, P Bruhns, Y Saeys, H Hammad… - Nature Reviews …, 2014 - nature.com
Dendritic cells (DCs) and macrophages use various receptors to recognize foreign antigens
and to receive feedback control from adaptive immune cells. Although it was long believed …

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

N van Montfoort, MG Camps, S Khan… - Proceedings of the …, 2009 - National Acad Sciences
Dendritic cells (DCs) are crucial for priming of naive CD8+ T lymphocytes to exogenous
antigens, so-called “cross-priming.” We report that exogenous protein antigen can be …