The serine/threonine kinase mechanistic target of rapamycin (mTOR) plays a pivotal role in
the regulation of cell proliferation, survival, and motility in response to availability of energy …

The mechanistic target of rapamycin (mTOR) is involved in the regulation of cellular growth,
proliferation, lipid synthesis, and protein translation. The mTOR pathway involves two …

The epidermis, the outmost layer of the skin, is a stratified squamous epithelium that protects
the body from the external world. The epidermis and its appendages need constantly renew …

PhosphoInositide-3 Kinase (PI3K) represents a family of different classes of kinases which
control multiple biological processes in mammalian cells, such as cell growth, proliferation …

The dysregulated phosphatidylinositol-3-kinase (PI3K)-Akt-mammalian target of rapamycin
(mTOR) signaling pathway has been implicated in various immune-mediated inflammatory …

The mammalian or mechanistic target of rapamycin (mTOR) and associated phosphatidyl-
inositiol 3-kinase (PI3K)/protein kinase B (Akt) pathways regulate cell growth, differentiation …

In this short communication we are providing insight about the regulatory role of the
phosphatidylinositol 3-kinase (PI3K)-AKT-mammalian target of rapamycin (mTOR) kinase …

The mechanistic/mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a
central regulator for human physiological activity. Deregulated mTOR signaling is implicated …

Psoriasis is a frequent and often severe inflammatory skin disease, characterized by altered
epidermal homeostasis. Since we found previously that Akt/mTOR signaling is …

Although modern biologics targeting different inflammatory mediators show promising
therapeutic success, comprehensive knowledge about the molecular events in psoriatic …