Although some of the redox changes that occur in biological components may result in
deleterious events, this process has recently been tackled as a modulatory event. Advances …

Oxidative stress is presumed to be involved in the pathogenesis of many diseases, including
cardiovascular disease. However, oxidants are also generated in healthy cells, and …

Oxidative stress has almost universally and unequivocally been implicated in the
pathogenesis of all major diseases, including those of the cardiovascular system. Oxidative …

Post-translational modifications (PTMs) generally refer to covalent and enzymatic
modifications of proteins during or after protein biosynthesis, as well as during cleavage or …

Spatiotemporal regulation of the activity of a vast array of intracellular proteins and signaling
pathways by reactive oxygen species (ROS) governs normal cardiovascular function …

The present review summarizes the beneficial and detrimental roles of reactive oxygen
species in myocardial ischemia/reperfusion injury and cardioprotection. In the first part, the …

Significance: Mitochondria-derived reactive oxygen species (mtROS) are by-products of
normal physiology that may disrupt cellular redox homeostasis on a regular basis …

Proteins succumb to numerous post-translational modifications (PTMs). These relate to
enzymatic or non-enzymatic reactions taking place in either the intracellular or extracellular …

Reactive oxygen species (ROS) are subcellular messengers in gene regulatory and signal
transduction pathways. In pathological situations, ROS accumulate due to excessive …

Reduction oxidation (REDOX) reaction is crucial in life activities, and its dynamic balance is
regulated by ROS. Reactive oxygen species (ROS) is associated with a variety of metabolic …