Modulation of RANKL and osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis in response to disease‐modifying antirheumatic drug …

D Haynes, T Crotti, H Weedon… - Arthritis Care & …, 2008 - Wiley Online Library
Modulation of RANKL and osteoprotegerin expression in synovial tissue from patients with
rheumatoid arthritis in response to disease‐modifying antirheumatic drug treatment and …

Anti–tumor necrosis factor therapy increases synovial osteoprotegerin expression in rheumatoid arthritis

AI Catrina, E Klint, S Ernestam… - … : Official Journal of …, 2006 - Wiley Online Library
Objective Treatment of rheumatoid arthritis (RA) with tumor necrosis factor (TNF)–blocking
agents, including etanercept and infliximab, has resulted in reductions in the radiographic …

Cytokine‐controlled RANKL and osteoprotegerin expression by human and mouse synovial fibroblasts: Fibroblast‐mediated pathologic bone resorption

M Tunyogi‐Csapo, K Kis‐Toth… - … : Official Journal of …, 2008 - Wiley Online Library
Objective To determine whether proinflammatory cytokine treatment or the complete
absence of select cytokines modulates the expression of RANKL and osteoprotegerin (OPG) …

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction

PP Geusens, RBM Landewé, P Garnero… - Arthritis & …, 2006 - Wiley Online Library
Objective Rheumatoid arthritis (RA) is a chronic inflammatory disease that may result in
debilitating joint deformities with destruction of bone and cartilage. Inflammation is still …

The abundant synovial expression of the RANK/RANKL/Osteoprotegerin system in peripheral spondylarthritis is partially disconnected from inflammation

B Vandooren, T Cantaert, T Noordenbos… - … : Official Journal of …, 2008 - Wiley Online Library
Abstract Objective Spondylarthritis (SpA) and rheumatoid arthritis (RA) have different
patterns of bone damage, with more pronounced bone erosions in RA. The RANK/RANKL …

Osteoprotegerin and receptor activator of nuclear factor-kappaB ligand mRNA expression in patients with rheumatoid arthritis and healthy controls.

A Vanderborght, L Linsen, M Thewissen… - The Journal of …, 2004 - jrheum.org
OBJECTIVE: To further understand the role of osteoprotegerin (OPG) and receptor activator
of nuclear factor-kappaB ligand (RANK-L) in rheumatoid arthritis (RA), we studied the levels …

[引用][C] The RANK/RANKL/osteoprotegerin system in rheumatoid arthritis: new insights from animal models

E Neumann, S Gay… - Arthritis & Rheumatism …, 2005 - Wiley Online Library
Rheumatoid arthritis (RA) is characterized by inflammatory synovitis and progressive
destruction of cartilage and bone. While the mechanisms of cartilage destruction in RA have …

[PDF][PDF] Imbalanced expression of RANKL and osteoprotegerin mRNA in pannus tissue of rheumatoid arthritis

M Ainola, J Mandelin, M Liljestrom… - Clinical and …, 2008 - clinexprheumatol.org
Imbalanced expression of RANKL and osteoprotegerin mRNA in pannus tissue of
rheumatoid arthritis Page 1 Clinical and Experimental Rheumatology 2008; 26: 240-246 …

Variability of RANKL and osteoprotegerin staining in synovial tissue from patients with active rheumatoid arthritis: quantification using color video image analysis.

TN Crotti, MJ Ahern, K Lange, H Weedon… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To assess the interpatient, interbiopsy, and intrabiopsy variability of receptor
activator of nuclear factor kB ligand (RANKL) and osteoprotegerin (OPG) immunostaining …

Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis

D Makrygiannakis, E af Klint, SB Catrina… - … : Official Journal of …, 2006 - Wiley Online Library
Objective Intraarticular corticosteroids are frequently used as successful adjuvant therapy for
inflammatory arthritides, but little is known about their effects on molecules that regulate …