2 METHODS Methods used in the Global Project have been extensively described. For this
report, therefore, the methods are only summarized, while changes and new developments …

Guidelines for surveillance of drug resistance in tuberculosis Page 1 Guidelines for surveillance
of drug resistance in tuberculosis FOURTH EDITION Page 2 Page 3 Guidelines for surveillance …

Summary Background The Global Project on Anti-Tuberculosis Drug Resistance has been
gathering data since 1994. This study provides the latest data on the extent of drug …

Background Drug-resistant tuberculosis threatens efforts to control the disease. This report
describes the prevalence of resistance to four first-line drugs in 35 countries participating in …

The emergence of strains of Mycobacterium tuberculosis that are resistant to
antimycobacterial agents is a worldwide problem whose global magnitude is not well …

Drug-resistant tuberculosis has been reported since the early days of the introduction of
chemotherapy. However, most of the evidence was limited to developed countries. In 1992 …

Background The burden of tuberculosis is compounded by drug-resistant forms of the
disease. This study aimed to analyse data on antituberculosis drug resistance gathered by …

There is a suggestion that drug resistance rates decreased in developing countries over the
period 1962–1985, while recent data suggest that resistance may be increasing. The initial …

Resistance to antituberculosis drugs is caused by poor management of tuberculosis control.
It gives rise to treatment failure, relapse, further transmission of resistant tuberculosis, and …

The Global Project has actively catalysed changes in policies and programmes for TB
control. DOTS-Plus, a strategy for the management of drug-resistant TB, was a result of …