An overview of the bacterial contribution to Crohn disease pathogenesis

MH Alhagamhmad, AS Day… - Journal of Medical …, 2016 - microbiologyresearch.org
Crohn disease (CD) is a chronic inflammatory condition primarily affecting the gastro-
intestinal tract and is characterized by reduced bacterial diversity. The exact cause of …

The role of microbes in Crohn's disease

PB Eckburg, DA Relman - Clinical Infectious Diseases, 2007 - academic.oup.com
Despite decades of research, the etiology of Crohn's disease (CD) remains unknown. Its
pathogenesis may involve a complex interplay between host genetics, immune dysfunction …

[HTML][HTML] Infectious etiopathogenesis of Crohn's disease

J Carrière, A Darfeuille-Michaud… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Important advances during the last decade have been made in understanding the complex
etiopathogenesis of Crohn's disease (CD). While many gaps in our knowledge still exist, it …

Role of gut microbiota in Crohn's disease

PI Baker, DR Love, LR Ferguson - Expert review of …, 2009 - Taylor & Francis
Crohn's disease (CD), a form of inflammatory bowel disease (IBD), provides a complex
model of host–microbe interactions underpinning disease pathogenesis. Although there is …

[HTML][HTML] Pathogenesis of Crohn's disease: Bug or no bug

MM Bosca-Watts, J Tosca, R Anton… - World journal of …, 2015 - ncbi.nlm.nih.gov
The possibility of an infectious origin in inflammatory bowel disease (IBD) has been
postulated since the first description of Crohn's disease (CD). Many observations implicate …

Bacterial imbalance in Crohn's disease

U Hofer - Nature Reviews Microbiology, 2014 - nature.com
Bacterial imbalance in Crohn's disease | Nature Reviews Microbiology Skip to main content
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[HTML][HTML] Evidence for the involvement of infectious agents in the pathogenesis of Crohn's disease

G De Hertogh, J Aerssens, KP Geboes… - World journal of …, 2008 - ncbi.nlm.nih.gov
Many advances have been made in the understanding of Crohn's disease (CD)
pathogenesis during the last decade. CD is currently seen as a predominantly T-lymphocyte …

[HTML][HTML] Mechanisms of microbe–host interaction in Crohn's disease: dysbiosis vs. pathobiont selection

LF Buttó, M Schaubeck, D Haller - Frontiers in immunology, 2015 - frontiersin.org
Crohn's disease (CD) is a systemic chronic inflammatory condition mainly characterized by
discontinuous transmural pathology of the gastrointestinal tract and frequent extraintestinal …

[HTML][HTML] Intestinal microbiota and the innate immune system–a crosstalk in Crohn's disease pathogenesis

LM Haag, B Siegmund - Frontiers in immunology, 2015 - frontiersin.org
Crohn's disease (CD) is a chronic, relapsing inflammatory disorder that can occur anywhere
along the gastrointestinal tract. The precise etiology of CD is still unclear but it is widely …

Bacteria in Crohn's disease: mechanisms of inflammation and therapeutic implications

RB Sartor - Journal of clinical gastroenterology, 2007 - journals.lww.com
Microbial agents are implicated in each of the most prevalent etiologic hypotheses of
Crohn's disease. Although chronic infection with a specific, persistent pathogen cannot be …