Use of low-titer O-positive whole blood in female trauma patients: a literature review, qualitative multidisciplinary analysis of risk/benefit, and guidelines for its use as a …
TW Clements, JM Van Gent, N Menon… - Journal of the …, 2023 - journals.lww.com
Background: Whole blood transfusion is associated with benefits including improved
survival, coagulopathy, and decreased transfusion requirements. The majority of whole …
survival, coagulopathy, and decreased transfusion requirements. The majority of whole …
Not as “D” eadly as once thought–the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma
MH Yazer, G Panko, JB Holcomb, A Kaplan… - …, 2023 - Taylor & Francis
The use of blood products to resuscitate injured and massively bleeding patients in the
prehospital and early in-hospital phase of the resuscitation is increasing. Using group O red …
prehospital and early in-hospital phase of the resuscitation is increasing. Using group O red …
Prehospital low-titer cold-stored whole blood: philosophy for ubiquitous utilization of O-positive product for emergency use in hemorrhage due to injury
AC McGinity, CS Zhu, L Greebon… - Journal of Trauma …, 2018 - journals.lww.com
The mortality from hemorrhage in trauma patients remains high. Early balanced
resuscitation improves survival. These truths, balanced with the availability of local …
resuscitation improves survival. These truths, balanced with the availability of local …
Safety profile and impact of low-titer group O whole blood for emergency use in trauma
J Williams, N Merutka, D Meyer, Y Bai… - Journal of Trauma …, 2020 - journals.lww.com
PURPOSE Following US military implementation of a cold-stored whole blood program,
several US trauma centers have begun incorporating uncrossmatched, group O cold-stored …
several US trauma centers have begun incorporating uncrossmatched, group O cold-stored …
Is Low-Titer Group O Whole Blood Truly a Universal Blood Product?
JB Brill, KM Mueck, B Tang, M Sandoval… - Journal of the …, 2023 - journals.lww.com
BACKGROUND: Whole blood was historically transfused as a type-specific product. Given
recent advocacy for low-titer group O whole blood (LTOWB) as a universal blood product …
recent advocacy for low-titer group O whole blood (LTOWB) as a universal blood product …
Survey of policies at US hospitals on the selection of RhD type of low‐titer O whole blood for use in trauma resuscitation
S Clayton, CM Leeper, MH Yazer, PC Spinella - Transfusion, 2024 - Wiley Online Library
Background Low‐titer group O whole blood (LTOWB) use is increasing due to data
suggesting improved outcomes and safety. One barrier to use is low availability of RhD …
suggesting improved outcomes and safety. One barrier to use is low availability of RhD …
Safety of uncrossmatched type-O red cells for resuscitation from hemorrhagic shock
RP Dutton, D Shih, BB Edelman, J Hess… - Journal of Trauma and …, 2005 - journals.lww.com
Background: Uncrossmatched type-O packed red blood cells (UORBC) are recommended
for immediate transfusion in hemorrhaging trauma patients. The potential for …
for immediate transfusion in hemorrhaging trauma patients. The potential for …
Ethical considerations in the use of RhD‐positive blood products in trauma
JR Malone - Transfusion, 2024 - Wiley Online Library
Background Prehospital and early in‐hospital use of low titer group O whole blood (LTOWB)
for life‐threatening bleeding has been independently associated with improved survival …
for life‐threatening bleeding has been independently associated with improved survival …
Clinical outcomes among low‐titer group O whole blood recipients compared to recipients of conventional components in civilian trauma resuscitation
BACKGROUND The serological safety of transfusing≤ 4 units of low titer group O whole
blood (LTOWB) in civilian trauma patients has been demonstrated. This study investigated …
blood (LTOWB) in civilian trauma patients has been demonstrated. This study investigated …
Another piece of the hemolytic disease of the fetus and newborn puzzle after RhD-positive transfusion in trauma resuscitation: the proportion of pregnant women who …
MH Yazer, SP Emery, DJ Triulzi, P Spinella… - Trauma Surgery & …, 2024 - tsaco.bmj.com
Background After the transfusion of RhD-positive red blood cell (RBC)-containing products
to an RhD-negative woman of childbearing potential (WCP) during trauma resuscitation …
to an RhD-negative woman of childbearing potential (WCP) during trauma resuscitation …