Circular RNA: An emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines
Circular RNAs (circRNA) is a class of natural (biogenic) or synthetic closed RNA without 5′
or 3′ ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA …
or 3′ ends. Meanwhile, their unique covalently-closed structures of circRNA prevent RNA …
The design and synthesis of circular RNAs
P Obi, YG Chen - Methods, 2021 - Elsevier
Circular RNAs (circRNAs) are a novel class of RNAs distinguished by their single-stranded,
covalently-closed topology. Although initially perceived as rare byproducts of aberrant …
covalently-closed topology. Although initially perceived as rare byproducts of aberrant …
[HTML][HTML] Advances in circular RNA and its applications
X Zhao, Y Zhong, X Wang, J Shen… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Circular RNA (circRNA) is a novel endogenous non-coding RNA (ncRNA) that, like
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …
microRNA (miRNA), is a rapidly emerging RNA research topic. CircRNA, unlike traditional …
Circular RNA: an important player with multiple facets to regulate its parental gene expression
T Shao, Y Pan, X Xiong - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Circular RNAs (circRNAs), a novel type of endogenous RNAs with covalently closed-loop
structures, have become a new research hotspot in the RNA world. Their diversity, stability …
structures, have become a new research hotspot in the RNA world. Their diversity, stability …
Deep insights in circular RNAs: from biogenesis to therapeutics
Circular RNAs (circRNAs) have emerged as a universal novel class of eukaryotic non-
coding RNA (ncRNA) molecules and are becoming a new research hotspot in RNA biology …
coding RNA (ncRNA) molecules and are becoming a new research hotspot in RNA biology …
Clinical delivery of circular RNA: lessons learned from RNA drug development
Circular RNAs (circRNA) represent a distinct class of covalently closed-loop RNA molecules,
which play diverse roles in regulating biological processes and disease states. The …
which play diverse roles in regulating biological processes and disease states. The …
The emerging roles and functions of circular RNAs and their generation
CY Yu, HC Kuo - Journal of biomedical science, 2019 - Springer
Circular RNAs (circRNAs) are closed long non-coding RNAs, in which the 5'and 3'termini
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …
are covalently linked by back-splicing of exons from a single pre-mRNA. Emerging evidence …
Circular RNA and its mechanisms in disease: from the bench to the clinic
B Han, J Chao, H Yao - Pharmacology & therapeutics, 2018 - Elsevier
The emerging recognition of the functional roles of circular RNAs (circRNAs) has given rise
to a new perspective regarding our understanding of cellular physiology and disease …
to a new perspective regarding our understanding of cellular physiology and disease …
[HTML][HTML] Review on circular RNAs and new insights into their roles in cancer
X Tang, H Ren, M Guo, J Qian, Y Yang, C Gu - … and structural biotechnology …, 2021 - Elsevier
Circular RNAs (circRNAs) are a very interesting class of conserved single-stranded RNA
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
molecules derived from exonic or intronic sequences by precursor mRNA back-splicing …
Targeting circular RNAs as a therapeutic approach: current strategies and challenges
Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …
Increasing evidence suggests that circRNAs play important roles in many cellular processes …