Homocysteine: a biomarker in neurodegenerative diseases
W Herrmann, R Obeid - Clinical chemistry and laboratory medicine, 2011 - degruyter.com
Diseases of the central nervous system are found in patients with severe
hyperhomocysteinemia (HHcy). Epidemiological studies show a positive, dose-dependent …
hyperhomocysteinemia (HHcy). Epidemiological studies show a positive, dose-dependent …
The contribution of homocysteine metabolism disruption to endothelial dysfunction: state-of-the-art
R Esse, M Barroso, I Tavares de Almeida… - International journal of …, 2019 - mdpi.com
Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …
metabolism of the essential amino acid methionine. Hcy is considered a risk factor for …
[HTML][HTML] Homocysteine, hyperhomocysteinemia and vascular contributions to cognitive impairment and dementia (VCID)
AH Hainsworth, NE Yeo, EM Weekman… - Biochimica et Biophysica …, 2016 - Elsevier
Homocysteine is produced physiologically in all cells, and is present in plasma of healthy
individuals (plasma [HCy]: 3–10 μM). While rare genetic mutations (CBS, MTHFR) cause …
individuals (plasma [HCy]: 3–10 μM). While rare genetic mutations (CBS, MTHFR) cause …
The role of homocysteine levels as a risk factor of ischemic stroke events: A systematic review and meta-analysis
RT Pinzon, VO Wijaya, V Veronica - Frontiers in Neurology, 2023 - frontiersin.org
Introduction Among numerous risk factors, homocysteine (Hcy) has been linked to cerebral
infarction; however, results have been inconsistent. This review aimed to conduct a meta …
infarction; however, results have been inconsistent. This review aimed to conduct a meta …
Homocysteine, intracellular signaling and thrombotic disorders
N Dionisio, I Jardín, GM Salido… - Current Medicinal …, 2010 - ingentaconnect.com
Homocysteine, a sulphur-containing amino acid derived from methionine, has been
presented as an independent risk factor for cardiovascular disorders, including …
presented as an independent risk factor for cardiovascular disorders, including …
Elevated homocysteine levels are associated with the metabolic syndrome and cardiovascular events in hypertensive patients
BACKGROUND Hyperhomocysteinemia and the metabolic syndrome are established
cardiovascular risk factors and are frequently associated with hypertension. The relationship …
cardiovascular risk factors and are frequently associated with hypertension. The relationship …
Roles of homocysteine in cell metabolism: old and new functions
MÁ Medina, JL Urdiales… - European journal of …, 2001 - Wiley Online Library
Mild hyperhomocysteinemia has been suggested as a new, independent risk factor for
cardiovascular disease. This fact has produced a new, increased interest in the study of …
cardiovascular disease. This fact has produced a new, increased interest in the study of …
[HTML][HTML] Hyperhomocysteinemia
P Son, L Lewis - StatPearls [Internet], 2022 - ncbi.nlm.nih.gov
Objectives: Review the indications for obtaining a homocysteine level. Summarize who
should receive treatment for hyperhomocysteinemia. Identify patients who would have …
should receive treatment for hyperhomocysteinemia. Identify patients who would have …
Hyperhomocysteinemia and oxidative stress: time for a reality check?
DW Jacobsen - Arteriosclerosis, thrombosis, and vascular biology, 2000 - Am Heart Assoc
Oxidative stress due to the production of intracellular and extracellular reactive oxygen
species may be a major player in the pathogenesis of cardiovascular and other diseases …
species may be a major player in the pathogenesis of cardiovascular and other diseases …
The metabolism and significance of homocysteine in nutrition and health
An association between arteriosclerosis and homocysteine (Hcy) was first demonstrated in
1969. Hcy is a sulfur containing amino acid derived from the essential amino acid …
1969. Hcy is a sulfur containing amino acid derived from the essential amino acid …