[HTML][HTML] Homocysteine induced cerebrovascular dysfunction: a link to Alzheimer's disease etiology

PK Kamat, JC Vacek, A Kalani… - The open neurology …, 2015 - ncbi.nlm.nih.gov
A high serum level of homocysteine, known as hyperhomocystenemia (HHcy) is associated
with vascular dysfunction such as altered angiogenesis and increased membrane …

Homocysteine metabolism and its relation to health and disease

KT Williams, KL Schalinske - Biofactors, 2010 - Wiley Online Library
Homocysteine is a metabolic intermediate in methyl group metabolism that is dependent on
a number of nutritional B‐vitamin cofactors. An emerging aspect of homocysteine …

Metabolism of homocysteine and its relationship with cardiovascular disease

B Aguilar, JC Rojas, MT Collados - Journal of thrombosis and thrombolysis, 2004 - Springer
Hyperhomocysteinemia, or the rise of plasmatic homocysteine levels above 15 μg/dL, is
accepted nowadays as an independent risk factor for cardiovascular disease in men and …

Hypothesis: hyperhomocysteinemia is an indicator of oxidant stress

M Hoffman - Medical hypotheses, 2011 - Elsevier
Elevated plasma homocysteine levels are associated with an increased risk of
atherosclerosis and thrombosis, as well as a variety of other pathologies such as birth …

The central nervous system in animal models of hyperhomocysteinemia

AM Troen - Progress in Neuro-Psychopharmacology and …, 2005 - Elsevier
Growing epidemiological evidence of associations between mildly elevated plasma
homocysteine with age-related cognitive impairment, neurodegenerative and …

Role of homocysteine in age-related vascular and non-vascular diseases

L Parnetti, T Bottiglieri, D Lowenthal - Aging Clinical and Experimental …, 1997 - Springer
Homocysteine (Hcy) may represent a metabolic link in the pathogenesis of atherosclerotic
vascular diseases and old-age dementias. Hyperhomocysteinemia is an independent risk …

Biochemistry of homocysteine in health and diseases

S Ramakrishnan, KN Sulochana, S Lakshmi, R Selvi… - 2006 - nopr.niscpr.res.in
The amino acid homocysteine (Hcy), formed from methionine has profound importance in
health and diseases. In normal circumstances, it is converted to cysteine and partly …

The current status of homocysteine as a risk factor for cardiovascular disease: a mini review

SG Chrysant, GS Chrysant - Expert review of cardiovascular …, 2018 - Taylor & Francis
Introduction: Hyperhomocysteinemia has been considered as a risk factor for systemic
atherosclerosis, cardiovascular disease (CVD) and stroke and many epidemiologic and …

Association of homocysteine level with risk of stroke: A dose–response meta-analysis of prospective cohort studies

X Wu, Q Zhou, Q Chen, Q Li, C Guo, G Tian… - Nutrition, Metabolism …, 2020 - Elsevier
Abstract Background and aims Homocysteine (Hcy) level has been increasingly linked with
stroke and ischemic stroke (IS). However, a dose–response meta-analysis of prospective …

[HTML][HTML] The link between hyperhomocysteinemia and hypomethylation: Implications for cardiovascular disease

M Barroso, DE Handy, R Castro - … of Inborn Errors of Metabolism and …, 2019 - SciELO Brasil
Increased levels of homocysteine have been established as a risk factor for cardiovascular
disease (CVD) by mechanisms still incompletely defined. S-Adenosylhomocysteine (SAH) is …