Severe hyperhomocysteinemia (50–200 μM) often presents itself with acute neuronal
dysfunction including seizures and psychosis. Its moderate form (15–50 μM) is associated …

Increased levels of homocysteine have been established as a risk factor for cardiovascular
disease (CVD) by mechanisms still incompletely defined. S-Adenosylhomocysteine (SAH) is …

Introduction: Hyperhomocysteinemia has been considered as a risk factor for systemic
atherosclerosis, cardiovascular disease (CVD) and stroke and many epidemiologic and …

Homocysteine (Hcy) is an endogenous, non-structural protein, a sulfur-containing amino
acid emerging on the pathway of methionine and cysteine, actively involved in numerous …

Abstract Background and aims Homocysteine (Hcy) level has been increasingly linked with
stroke and ischemic stroke (IS). However, a dose–response meta-analysis of prospective …

Objective: To summarize recent developments in our understanding of homocysteine as a
clinically relevant and independent predictor of vaso-occlusive disease (including …

Hyperhomocysteinemia (HHcy) is a systemic medical condition and has been attributed to
multi-organ pathologies. Genetic, nutritional, hormonal, age and gender differences are …

Increased plasma homocysteine is a risk factor for several pathological disorders. The
present review focused on the role of homocysteine (Hcy) in different population groups …

Background: Hyperhomocysteinemia has been shown to be a mild independent risk factor
for premature atherosclerosis, and there is evidence of an increased rate of peripheral …

This study examined the association between elevated plasma homocysteine (Hcy) levels
and the risk of acute cerebral infarction in patients with carotid artery lesions. A total of 78 …