CMR-verified diffuse myocardial fibrosis is associated with diastolic dysfunction in HFpEF

MYM Su, LY Lin, YHE Tseng, CC Chang, CK Wu… - JACC: Cardiovascular …, 2014 - jacc.org
Objectives: The purpose of this study was to investigate diffuse myocardial fibrosis in
patients with systolic heart failure (SHF) and in patients with heart failure with preserved …

Relationship between focal and diffuse fibrosis assessed by CMR and clinical outcomes in heart failure with preserved ejection fraction

P Kanagala, ASH Cheng, A Singh, JN Khan… - JACC: Cardiovascular …, 2019 - jacc.org
Objectives: This study sought to assess the presence and extent of focal and diffuse fibrosis
in heart failure in patients with preserved ejection fraction (HFpEF) compared to …

[HTML][HTML] Associations and prognostic significance of diffuse myocardial fibrosis by cardiovascular magnetic resonance in heart failure with preserved ejection fraction

C Roy, A Slimani, C de Meester, M Amzulescu… - Journal of …, 2018 - Elsevier
Background Increased myocardial fibrosis may play a key role in heart failure with preserved
ejection fraction (HFpEF) pathophysiology. The study aim was to evaluate the presence …

Prognostic significance of quantitative assessment of focal myocardial fibrosis in patients with heart failure with preserved ejection fraction

S Kato, N Saito, H Kirigaya, D Gyotoku, N Iinuma… - International journal of …, 2015 - Elsevier
Background The aim of this study was to investigate the prognostic value of myocardial focal
fibrosis quantified by late gadolinium enhanced (LGE) magnetic resonance imaging (MRI) in …

Progression of myocardial fibrosis in nonischemic DCM and association with mortality and heart failure outcomes

A Mandawat, P Chattranukulchai, A Mandawat… - Cardiovascular …, 2021 - jacc.org
Objectives The purpose of this study was to assess whether the presence and extent of
fibrosis changes over time in patients with nonischemic, dilated cardiomyopathy (DCM) …

Influence of myocardial fibrosis on left ventricular diastolic function: noninvasive assessment by cardiac magnetic resonance and echo

A Moreo, G Ambrosio, B De Chiara, M Pu… - Circulation …, 2009 - Am Heart Assoc
Background—Fibrosis is a common end point of many pathological processes affecting the
myocardium and may alter myocardial relaxation properties. By measuring myocardial …

Prognostic Impact of Myocardial Interstitial Fibrosis in Non-Ischemic Heart Failure–Comparison Between Preserved and Reduced Ejection Fraction Heart Failure–

T Aoki, Y Fukumoto, K Sugimura, M Oikawa… - Circulation …, 2011 - jstage.jst.go.jp
Background: Although myocardial fibrosis plays an important role in the progression of heart
failure (HF), its prognostic impact still remains to be clarified. Methods and Results: A total of …

Interstitial fibrosis, functional status, and outcomes in heart failure with preserved ejection fraction: insights from a prospective cardiac magnetic resonance imaging …

F Duca, AA Kammerlander, C Zotter-Tufaro… - Circulation …, 2016 - Am Heart Assoc
Background—Myocardial extracellular volume (ECV) accumulation is one of the key
pathophysiologic features of heart failure with preserved ejection fraction (HFpEF). Our aims …

Evaluation of Diffuse Myocardial Fibrosis in Heart Failure With Cardiac Magnetic Resonance Contrast-Enhanced T1 Mapping

L Iles, H Pfluger, A Phrommintikul, J Cherayath… - Journal of the American …, 2008 - jacc.org
Objectives: The purpose of this study was to investigate a noninvasive method for
quantifying diffuse myocardial fibrosis with cardiac magnetic resonance imaging (CMRI) …

Absence of myocardial fibrosis predicts favorable long-term survival in new-onset heart failure: a cardiovascular magnetic resonance study

A Gulati, AG Japp, S Raza, BP Halliday… - Circulation …, 2018 - Am Heart Assoc
Background: Myocardial fibrosis, identified by late gadolinium enhancement cardiovascular
magnetic resonance, predicts outcomes in chronic heart failure (HF). Its prognostic …