Angiogenesis: a target for cancer therapy
The induction of neoangiogenesis is a critical step already present at the early stages of
tumor development and dissemination. The progressive identification of molecules playing a …
tumor development and dissemination. The progressive identification of molecules playing a …
Angiogenesis and antiangiogenic therapy
GW Sledge Jr, KD Miller - Current Problems in Cancer, 2002 - Elsevier
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Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue Search …
Elsevier logo Journals & Books Search RegisterSign in View PDF Download full issue Search …
The impact of anti-angiogenic agents on cancer therapy
D Marmé - Journal of cancer research and clinical oncology, 2003 - Springer
Initiation, development and malignant progression of tumors depend on multiple genetic
alterations as well as posttranscriptional and posttranslational modifications within the tumor …
alterations as well as posttranscriptional and posttranslational modifications within the tumor …
Vascular remodeling in cancer
The growth and dissemination of tumors rely on an altered vascular network, which supports
their survival and expansion and provides accessibility to the vasculature and a route of …
their survival and expansion and provides accessibility to the vasculature and a route of …
Angiogenic factors as potential drug target: efficacy and limitations of anti-angiogenic therapy
RN Gacche, RJ Meshram - Biochimica et Biophysica Acta (BBA)-Reviews …, 2014 - Elsevier
Formation of new blood vessels (angiogenesis) has been demonstrated to be a basic
prerequisite for sustainable growth and proliferation of tumor. Several growth factors …
prerequisite for sustainable growth and proliferation of tumor. Several growth factors …
Role of angiogenesis in tumor growth and metastasis
J Folkman - Seminars in oncology, 2002 - Elsevier
Angiogenesis is required for invasive tumor growth and metastasis and constitutes an
important point in the control of cancer progression. Its inhibition may be a valuable new …
important point in the control of cancer progression. Its inhibition may be a valuable new …
Novel therapeutic approaches for targeting tumor angiogenesis
AG Linkous, EM Yazlovitskaya - Anticancer research, 2012 - ar.iiarjournals.org
Current attempts to disrupt the complex process of tumor blood vessel formation are
predominantly focused on targeting the vascular endothelial growth factor (VEGF)–VEGFR …
predominantly focused on targeting the vascular endothelial growth factor (VEGF)–VEGFR …
Tumor angiogenesis as a therapeutic target
A Matter - Drug Discovery Today, 2001 - Elsevier
Angiogenesis–the formation of new blood vessels within a tumor (or many other tissue
types)–has become a hotbed of pharmacological research as well as industrial drug …
types)–has become a hotbed of pharmacological research as well as industrial drug …
Molecular mechanisms of tumor angiogenesis
S Ziyad, ML Iruela-Arispe - Genes & cancer, 2011 - journals.sagepub.com
Tumors have been recently recognized as aberrant organs composed of a complex mixture
of highly interactive cells that in addition to the cancer cell include stroma (fibroblasts …
of highly interactive cells that in addition to the cancer cell include stroma (fibroblasts …
Angiogenesis modulation in cancer research: novel clinical approaches
M Cristofanilli, C Charnsangavej… - Nature reviews Drug …, 2002 - nature.com
Angiogenesis—the formation of new blood vessels—is essential for tumour progression and
metastasis. Consequently, the modulation of tumour angiogenesis using novel agents has …
metastasis. Consequently, the modulation of tumour angiogenesis using novel agents has …