[HTML][HTML] Identification and validation of chemokine system-related genes in idiopathic pulmonary fibrosis

T Zhao, X Wu, X Zhao, K Yao, X Li, J Ni - Frontiers in Immunology, 2023 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressive interstitial lung
disease with limited therapeutic options. Recent studies have demonstrated that …

[HTML][HTML] Machine learning-based prediction of candidate gene biomarkers correlated with immune infiltration in patients with idiopathic pulmonary fibrosis

Y Zhang, C Wang, Q Xia, W Jiang, H Zhang… - Frontiers in …, 2023 - frontiersin.org
Objective This study aimed to identify candidate gene biomarkers associated with immune
infiltration in idiopathic pulmonary fibrosis (IPF) based on machine learning algorithms …

Development and validation of a novel gene signature for predicting the prognosis of idiopathic pulmonary fibrosis based on three epithelial-mesenchymal transition …

J Zheng, H Dong, T Zhang, J Ning, Y Xu, C Cai - Frontiers in Genetics, 2022 - frontiersin.org
Background: Increasing evidence has revealed that epithelial–mesenchymal transition
(EMT) and immunity play key roles in idiopathic pulmonary fibrosis (IPF). However …

Neutrophil-Related Gene Expression Signatures in Idiopathic Pulmonary Fibrosis: Implications for Disease Characteristic and Identification of Diagnostic Hub Genes

Y Lin, X Lai, T Lei, Y Qiu, Q Deng, Q Liu… - Journal of …, 2023 - Taylor & Francis
Background Idiopathic pulmonary fibrosis (IPF) is a disease with unclear etiology and a poor
prognosis. Although the involvement of neutrophils in IPF pathogenesis has been …

Transcriptomics in idiopathic pulmonary fibrosis unveiled: a new perspective from differentially expressed genes to therapeutic targets

W Hu, Y Xu - Frontiers in Immunology, 2024 - frontiersin.org
Background The underlying molecular pathways of idiopathic pulmonary fibrosis (IPF), a
progressive lung condition with a high death rate, are still mostly unknown. By using …

IPF-related new macrophage subpopulations and diagnostic biomarker identification-combine machine learning with single-cell analysis

H Zhang, Y Yang, Y Cao, J Guan - Respiratory Research, 2024 - Springer
Abstracts Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unknown etiology that
lacks a specific treatment. In IPF, macrophages play a key regulatory role as a major …

The combined model of CX3CR1-related immune infiltration genes to evaluate the prognosis of idiopathic pulmonary fibrosis

H Cai, S Chen, X Li, H Liu, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background High expression of chemokine (C-X3-C motif) receptor 1 (CX3CR1) was shown
to contribute to the progression of many fibrotic diseases. However, there is still no study for …

[HTML][HTML] Identification of diagnostic gene biomarkers related to immune infiltration in patients with idiopathic pulmonary fibrosis based on bioinformatics strategies

X Dai, Z Yang, W Zhang, S Liu, Q Zhao, T Liu… - Frontiers in …, 2022 - frontiersin.org
Objective: This study predicts the identification of potential diagnostic markers of idiopathic
pulmonary fibrosis (IPF) and analyzes the significance of immune cell infiltration in this …

[HTML][HTML] Identification of Hub Genes and Pathways Associated With Idiopathic Pulmonary Fibrosis via Bioinformatics Analysis

H Wan, X Huang, P Cong, M He, A Chen… - Frontiers in molecular …, 2021 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive disease whose etiology remains
unknown. The purpose of this study was to explore hub genes and pathways related to IPF …

Identification of CFH and FHL2 as biomarkers for idiopathic pulmonary fibrosis

X Liu, M Yang, J Li, H Liu, Y Dong, J Zheng… - Frontiers in …, 2024 - frontiersin.org
Background Idiopathic pulmonary fibrosis (IPF) is a fatal disease of unknown etiology with a
poor prognosis, characterized by a lack of effective diagnostic and therapeutic interventions …