FDA/Arthritis Foundation osteoarthritis drug development workshop recap: assessment of long-term benefit

JS Kim, S Borges, DJ Clauw, PG Conaghan… - Seminars in arthritis and …, 2022 - Elsevier
Objective To summarize proceedings of a workshop convened to discuss the current state of
science in the disease of osteoarthritis (OA), identify the knowledge gaps, and examine the …

[HTML][HTML] Recent advances in the treatment of osteoarthritis

S Grässel, D Muschter - F1000Research, 2020 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is one of the most debilitating diseases and is associated with a high
personal and socioeconomic burden. So far, there is no therapy available that effectively …

Disease-modifying osteoarthritis drugs: in vitro and in vivo data on the development of DMOADs under investigation

PSE Davies, SM Graham, RJ MacFarlane… - Expert opinion on …, 2013 - Taylor & Francis
Introduction: Osteoarthritis is a disabling affliction, and disease-modifying osteoarthritis
drugs (DMOADs) would be highly desirable adjuncts to symptomatic relief as they may delay …

Pharmaceutical therapy for osteoarthritis

DS Cheng, CJ Visco - PM&R, 2012 - Wiley Online Library
There are a variety of oral and topical pharmaceutical agents for the treatment of
osteoarthritis. To date there is no pharmacologic agent proved to prevent disease …

Intra-articular therapies for osteoarthritis

SP Yu, DJ Hunter - Expert opinion on pharmacotherapy, 2016 - Taylor & Francis
Introduction: Conventional medical therapies for osteoarthritis are mainly palliative in nature,
aiming to control pain and symptoms. Traditional intra-articular therapies are not …

Current interventions in the management of knee osteoarthritis

D Bhatia, T Bejarano, M Novo - Journal of Pharmacy and Bioallied …, 2013 - journals.lww.com
Osteoarthritis (OA) is progressive joint disease characterized by joint inflammation and a
reparative bone response and is one of the top five most disabling conditions that affects …

Osteoarthritis: a narrative review of molecular approaches to disease management

LA Salman, G Ahmed, SG Dakin, B Kendrick… - Arthritis Research & …, 2023 - Springer
Osteoarthritis (OA) is a chronic, progressive degenerative whole joint disease that affects the
articular cartilage, subchondral bone, ligaments, capsule, and synovium. While it is still …

Current models for development of disease-modifying osteoarthritis drugs

MJ Makarczyk, Q Gao, Y He, Z Li, MS Gold… - … Engineering Part C …, 2021 - liebertpub.com
Osteoarthritis (OA) is a painful and disabling disease that affects millions of people
worldwide. Symptom-alleviating treatments exist, although none with long-term efficacy …

Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions

Y Cho, S Jeong, H Kim, D Kang, J Lee… - … & molecular medicine, 2021 - nature.com
Osteoarthritis (OA) is the most common form of arthritis. It is characterized by progressive
destruction of articular cartilage and the development of chronic pain and constitutes a …

Commentary on recent therapeutic guidelines for osteoarthritis

M Cutolo, F Berenbaum, M Hochberg, L Punzi… - Seminars in arthritis and …, 2015 - Elsevier
Background Despite availability of international evidence-based guidelines for osteoarthritis
(OA) management, agreement on the different treatment modalities is lacking. Method A …