Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS

MA Jacobson, WL Drew, J Feinberg… - Journal of Infectious …, 1991 - academic.oup.com
Infections caused by cytomegalovirus (CMV) resistantin vitroto ganciclovir, defined as
requiring> 6 µmol of ganciclovir for ED50 have developed in some AIDS patients with …

Incidence of foscarnet resistance and cidofovir resistance in patients treated for cytomegalovirus retinitis

DA Jabs, C Enger, M Forman, JP Dunn… - Antimicrobial agents …, 1998 - Am Soc Microbiol
Cytomegalovirus (CMV) retinitis is a common opportunistic infection in patients with AIDS.
With long-term therapy for CMV retinitis, resistant CMV may develop. In a prospective study …

Foscarnet treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome

MA Jacobson, JJ O'Donnell, J Mills - Antimicrobial agents and …, 1989 - Am Soc Microbiol
Ten patients with acquired immunodeficiency syndrome with newly diagnosed
cytomegalovirus (CMV) retinitis were treated with an induction regimen of intravenous …

Combination ganciclovir and foscarnet in the treatment of clinically resistant cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome

BD Kuppermann, M Flores-Aguilar… - Archives of …, 1993 - jamanetwork.com
Objective: To assess the clinical response and patient tolerance to daily infusions of both
ganciclovir sodium and foscarnet sodium for the treatment of clinically resistant …

Cytomegalovirus (CMV) resistance in patients with CMV retinitis and AIDS treated with oral or intravenous ganciclovir

WL Drew, MJ Stempien, J Andrews… - The Journal of …, 1999 - academic.oup.com
Abstract Treatment of cytomegalovirus (CMV) retinitis with oral ganciclovir results in
relatively low plasma concentrations of drug, which theoretically could cause more frequent …

Cytomegalovirus retinitis and viral resistance: ganciclovir resistance

DA Jabs, C Enger, JP Dunn, M Forman… - The Journal of …, 1998 - academic.oup.com
Cytomegalovirus (CMV) retinitis is among the most common opportunistic infections in
patients with AIDS and a substantial cause of visual loss. With long-term therapy, resistant …

Phase II dose-ranging trial of foscarnet salvage therapy for cytomegalovirus retinitis in AIDS patients intolerant of or resistant to ganciclovir (ACTG Protocol 093)

MA Jacobson, M Wulfsohn, JE Feinberg, R Davis… - AIDS, 1994 - journals.lww.com
Objective: To document response to foscarnet salvage therapy in patients with
cytomegalovirus (CMV) retinitis who are intolerant of or resistant to ganciclovir. Methods …

Combined and alternating ganciclovir and foscarnet in acute and maintenance therapy of human immunodeficiency virus-related cytomegalovirus encephalitis …

M Peters, U Timm, D Schürmann, HD Pohlel… - The clinical …, 1992 - Springer
Cytomegalovirus (CMV) causes life-threatening disseminated infections and in particular
vision-threatening infections of the retina in patients with the acquired immunodeficiency …

Randomized phase I trial of two different combination foscarnet and ganciclovir chronic maintenance therapy regimens for AIDS patients with cytomegalovirus retinitis …

MA Jacobson, F Kramer, Y Bassiakos… - Journal of Infectious …, 1994 - academic.oup.com
AIDS patients with newly diagnosed cytomegalovirus (CMV) retinitis who had just completed
a 14-day course of ganciclovir induction therapy were randomly assigned to an alternating …

Cytomegalovirus retinitis and viral resistance: prevalence of resistance at diagnosis, 1994

DA Jabs, JP Dunn, C Enger, M Forman… - Archives of …, 1996 - jamanetwork.com
Objective: To determine the prevalence of cytomegalovirus (CMV) isolates resistant to
ganciclovir sodium or foscarnet sodium at the time of diagnosis of CMV retinitis, prior to the …