The incidence and mortality of heart disease are the highest among all diseases all over the
world, and are still increasing with a world wide rise in living standards. To find effective …

Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to
ischemia in the corresponding myocardial territory which generally results in myocardial …

Experimental studies have demonstrated that reperfusion is associated with a host of
distinctive pathophysiologic derangements, the most important of which are reperfusion …

Reperfusion, without doubt, is the most effective way to treat the ischaemic myocardium.
Late reperfusion may however cause further damage. Myocardial production of oxygen free …

While some investigators recognize “reperfusion-induced injury” as an important component
of the overall injury that occurs during ischemia and reperfusion, others question its …

Abstract Ischemia/reperfusion (I/R) injury is an inflammatory condition that is characterized
by innate immunity and an adaptive immune response. This review is focused on the acute …

Since the initial description of the phenomenon by Jennings et al 50 years ago, our
understanding of the underlying mechanisms of reperfusion injury has grown significantly …

Ischemia reperfusion (IR), present in myocardial infarction or extremity injuries, is a major
clinical issue and leads to substantial tissue damage. Molecular mechanisms underlying IR …

Acute myocardial infarction (MI) is a major cause of death and disability worldwide. In
patients with MI, the treatment of choice for reducing acute myocardial ischemic injury and …

Ischemia-reperfusion damage is a complex pathological process that begins with tissue
anoxia and continues with the production of free oxygen radicals, expanding with the …