The genomic landscape of adult T cell leukemia/lymphoma

C Vicente, J Cools - Nature genetics, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus
type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large …

Integrated molecular analysis of adult T cell leukemia/lymphoma

K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi… - Nature …, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

AG Rowan, R Dillon, A Witkover… - Blood, The Journal …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy caused
by human T-cell leukemia virus type-1 (HTLV-1). ATL is preceded by decades of chronic …

Genetic alterations in adult T-cell leukemia/lymphoma: novel discoveries with clinical and biological significance

S Sakihama, K Karube - Cancers, 2022 - mdpi.com
Simple Summary In recent years, many researchers have devoted their efforts to clarifying
the genomic aberrations of adult T-cell leukemia/lymphoma (ATLL), and the overview of …

Targeted deep sequencing reveals clonal and subclonal mutational signatures in Adult T-cell leukemia/lymphoma and defines an unfavorable indolent subtype

A Marçais, L Lhermitte, M Artesi, C Laurent, K Durkin… - Leukemia, 2021 - nature.com
Adult T-cell leukemia/lymphoma (ATL) carries a poor prognosis even in indolent subtypes.
We performed targeted deep sequencing combined with mapping of HTLV-1 proviral …

Genetic profile of adult T‐cell leukemia/lymphoma in Okinawa: Association with prognosis, ethnicity, and HTLV‐1 strains

S Sakihama, K Morichika, R Saito, M Miyara… - Cancer …, 2021 - Wiley Online Library
Genetic alterations in adult T‐cell leukemia/lymphoma (ATLL), a T‐cell malignancy
associated with HTLV‐1, and their clinical impacts, especially from the perspective of viral …

Adult T-cell leukemia/lymphoma: a problem abroad and at home

C Dittus, JM Sloan - Hematology/Oncology Clinics, 2017 - hemonc.theclinics.com
Adult T-cell leukemia/lymphoma (ATLL) is a severe, yet fascinating, disease that develops in
a small proportion of individuals who are chronically infected with human T-cell lymphotropic …

Genetic alterations in adult T‐cell leukemia/lymphoma

Y Kogure, K Kataoka - Cancer science, 2017 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATL) is a peripheral T‐cell neoplasm with a dismal
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …

Potential for molecular targeted therapy for adult T-cell leukemia/lymphoma

M Faris - International Reviews of Immunology, 2008 - Taylor & Francis
Adult T-cell leukemia/lymphoma is an aggressive lymphoproliferative disorder of CD4+ T
lymphocytes associated with human T-cell leukemia virus type 1 (HTLV-I) infection …

Adult T-cell leukemia-lymphoma

K Tsukasaki, K Tobinai - Rare Lymphomas, 2014 - Springer
Adult T-cell leukemia-lymphoma (ATL) is a distinct malignancy of CD4+/CD25+/CCR4+/
FoxP3+ or-Treg/TH2 cells etiologically associated with human T-cell lymphotropic virus type …