The degree of tumor load reduction after therapy is an important prognostic factor for
patients with CML. Conventional metaphase analysis has been considered to be the 'gold …

We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …

A substantial minority of patients with chronic myeloid leukaemia (CML) achieve a complete
response to treatment with interferon‐α (IFN‐α), defined as the disappearance of …

The fate of the leukaemic clone after bone marrow transplantation (BMT) for patients with
chronic myeloid leukaemia (CML) may determine the long-term prognosis. Several groups …

In patients with chronic myelogenous leukaemia (CML) treated by allogeneic bone marrow
transplantation (BMT), detection of residual leukaemic cells carrying the characteristic …

The monitoring of minimal residual disease (MRD) through low sensitivity real-time (RT)
polymerase chain reaction (PCR) analysis of BCR-ABL transcripts allows early detection of …

To test whether patients in remission after allogeneic bone marrow transplantation (BMT)
possess a pool of chronic myeloid leukemia (CML) cells that do not express BCR-ABL …

Forty-eight long-term disease-free chronic myelogenous leukemia (CML) patients, who had
received unmanipulated allogeneic bone marrow transplants (BMT) for eradication of the …

We identified 243 patients with Philadelphia (Ph) chromosome–positive chronic myeloid
leukemia (CML) who had BCR-ABL transcripts monitored by quantitative reverse …

For patients with chronic myeloid leukaemia, methods for monitoring response to treatment
have changed considerably in recent years. In the 1980s, the principal approach was …