We identified 243 patients with Philadelphia (Ph) chromosome–positive chronic myeloid
leukemia (CML) who had BCR-ABL transcripts monitored by quantitative reverse …

We performed a two-step polymerase chain reaction (PCR) to detect bcr-abl-specific mRNA
in 440 peripheral blood and/or bone marrow samples of 30 chronic myeloid leukemia (CML) …

Recent progress in the development of diagnostic techniques has greatly facilitated the
monitoring of minimal residual disease (MRD) in patients with hematologic neoplasia. The …

To determine the source of residual disease detected in patients with chronic myeloid
leukaemia (CML) in complete cytogenetic remission (n= 8) after treatment with interferon‐α …

Metaphase‐FISH was adopted for the detection of proliferating Philadelphia‐positive (Ph+)
residual leukaemic cells in 25 patients with chronic myeloid leukaemia treated with …

Serial assays of qualitative (multiplex and nested) and quantitative PCR were carried out for
detecting and estimating the level of BCR-ABL transcripts in 39 CML patients following bone …

Relapse of chronic myelogenous leukemia after bone marrow transplantation can be
detected by using clinical, cytogenetic, or molecular tools. A modification of the polymerase …

Increasing numbers of patients with chronic myeloid leukaemia (CML) treated with tyrosine
kinase inhibitors achieve undetectable levels of BCR‐ABL mRNA using sensitive …

Sixteen patients treated by allogeneic bone marrow transplantation (BMT) for chronic
myelogenous leukemia (CML) were evaluated by the polymerase chain reaction (PCR) for …

BACKGROUND AND OBJECTIVES: The most common translocation in chronic myeloid
leukemia (CML) t (9; 22)(q34; q22) produces the BCR/ABL fusion gene. We set up and …