Background Despite many studies on endoplasmic reticulum (ER) stress in patients with
various inflammatory diseases, there is scarce information on ER stress in patients with …

Introduction The significance of endoplasmic reticulum (ER) stress in asthma is unclear.
Here, we demonstrate that ER stress and the unfolded protein response (UPR) are related to …

Introduction: Endoplasmic reticulum (ER) stress has been considered to be an important
regulator of airway inflammation in the pathogenesis of bronchial asthma, but the …

The endoplasmic reticulum (ER) is a specialized organelle that plays a central role in
biosynthesis, correct protein folding, and posttranslational modifications of secretory and …

Background C/EBP homologous protein (Chop), a marker of endoplasmic reticulum (ER)
stress, exhibits aberrant expression patterns during asthma development. However, its exact …

Background The endoplasmic reticulum (ER) stress response participates in many chronic
inflammatory and autoimmune diseases. In the current study, we sought to examine the …

Asthma has long attracted extensive attention because of its recurring symptoms of
reversible airflow obstruction, airway hyperresponsiveness (AHR) and airway inflammation …

Chronic bronchitis and emphysema are pathologic features of chronic obstructive pulmonary
disease (COPD). Cigarette smoke (CS)-induced endoplasmic reticulum (ER) stress has …

Endoplasmic reticulum (ER) stress and consequent unfolded protein response (UPR) are
important in inflammation but have been poorly explored in asthma. We used a mouse …

Endoplasmic reticulum (ER) stress that disrupts ER function can occur in response to a wide
variety of cellular stress factors leads to the accumulation of unfolded and misfolded proteins …