Background Karyotype determination has a central role in the genetic workup of pregnancy
loss, as aneuploidy (trisomy and monosomy) and polyploidy (triploidy and tetraploidy) are …

Purpose In this study, we evaluated the feasibility of the combining CNV-seq and
quantitative fluorescence polymerase chain reaction (QF-PCR) for miscarriage analysis in …

Abstract Background Pregnancy loss affects 10%–15% of pregnancies and is caused by
several factors, maternal and fetal. Most common cause is chromosomal aneuploidy and …

Preimplantation genetic diagnosis (PGD) or embryo selection was first performed in 1989
using PCR for gender selection to avoid X-linked recessive disorder. However, there was a …

Objective: To determine the frequency and distribution of chromosome abnormalities in
women with early pregnancy failure (EPF) detected by cytogenetic testing on chorionic villus …

Numerical chromosome errors are known to be common in early human embryos and
probably make a significant contribution to early pregnancy loss and implantation failure in …

Objectives: To report our experience over the past 10 years of chorionic villi sampling (CVS)
prenatal diagnosis in a high-risk population for chromosomal anomalies, and to analyze …

Designed to minimize chances of transferring genetically abnormal embryos,
preimplantation genetic diagnosis (PGD) involves in vitro fertilization (IVF), embryo biopsy …

Balanced chromosomal rearrangements (CRs) are among the most common genetic
abnormalities in humans. In the present study, we have investigated the degree of …

STUDY QUESTION Are chromosome abnormalities detected at Day 3 post-fertilization
predominantly retained in structures of the blastocyst other than the inner cell mass (ICM) …