Critical roles of NLRP3 inflammasome in IL-1β secretion induced by Corynebacterium pseudotuberculosis in vitro
Z Zhou, H Li, S Tian, W Yi, Y Zhou, H Yang, X Li… - Molecular …, 2019 - Elsevier
Corynebacterium pseudotuberculosis is a prominent human and animal pathogen causing
chronic inflammatory diseases. Interleukin-1β (IL-1β) is involved in the response to such …
chronic inflammatory diseases. Interleukin-1β (IL-1β) is involved in the response to such …
Virulent Mycobacterium bovis Beijing Strain Activates the NLRP7 Inflammasome in THP-1 Macrophages
Y Zhou, SZA Shah, L Yang, Z Zhang, X Zhou, D Zhao - PLoS One, 2016 - journals.plos.org
Mycobacterium bovis is the causative agent of tuberculosis in a wide range of mammals,
including humans. Macrophages are the first line of host defense. They secrete …
including humans. Macrophages are the first line of host defense. They secrete …
Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis
A Dorhoi, G Nouailles, S Jörg, K Hagens… - European journal of …, 2012 - Wiley Online Library
As a hallmark of tuberculosis (TB), Mycobacterium tuberculosis (MTB) induces
granulomatous lung lesions and systemic inflammatory responses during active disease …
granulomatous lung lesions and systemic inflammatory responses during active disease …
Activation of an NLRP3 Inflammasome Restricts Mycobacterium kansasii Infection
CC Chen, SH Tsai, CC Lu, ST Hu, TS Wu, TT Huang… - PloS one, 2012 - journals.plos.org
Mycobacterium kansasii has emerged as an important nontuberculous mycobacterium
pathogen, whose incidence and prevalence have been increasing in the last decade. M …
pathogen, whose incidence and prevalence have been increasing in the last decade. M …
By regulating the NLRP3 Inflammasome can reduce the release of inflammatory factors in the co-culture model of tuberculosis H37Ra strain and rat microglia
Z Xie, H Hui, Q Yao, Y Duan, W Li, Y Cheng… - Frontiers in Cellular …, 2021 - frontiersin.org
Objective Tuberculosis infection of the Central Nervous System can cause severe
inflammation in microglia, and NLRP3 inflammasome is also an important source of …
inflammation in microglia, and NLRP3 inflammasome is also an important source of …
Mycobacterium tuberculosis protein ESAT‐6 is a potent activator of the NLRP3/ASC inflammasome
Summary Interleukin‐1β (IL‐1β) represents one of the most important mediators of
inflammation and host responses to infection. Mycobacterium tuberculosis (Mtb), the …
inflammation and host responses to infection. Mycobacterium tuberculosis (Mtb), the …
Inflammasomes in Mycobacterium tuberculosis‐Driven Immunity
S Wawrocki, M Druszczynska - Canadian Journal of Infectious …, 2017 - Wiley Online Library
The development of effective innate and subsequent adaptive host immune responses is
highly dependent on the production of proinflammatory cytokines that increase the activity of …
highly dependent on the production of proinflammatory cytokines that increase the activity of …
Mycobacterial PPE13 activates inflammasome by interacting with the NATCH and LRR domains of NLRP3
Y Yang, P Xu, P He, F Shi, Y Tang, C Guan… - The FASEB …, 2020 - Wiley Online Library
Pathogenic mycobacteria, such as Mycobacterium tuberculosis, Mycobacterium bovis, and
Mycobacterium marinum, can trigger NLRP3 inflammasome activation leading to maturation …
Mycobacterium marinum, can trigger NLRP3 inflammasome activation leading to maturation …
CXCL1 and CXCL2 regulate NLRP3 inflammasome activation via G-protein–coupled receptor CXCR2
M Boro, KN Balaji - The Journal of Immunology, 2017 - journals.aai.org
Inflammation is an extensively concerted process that confers protection to the host
encountering immune insult. The major inflammatory mediators include IL-1 family …
encountering immune insult. The major inflammatory mediators include IL-1 family …
Involvement of absent in melanoma 2 in inflammasome activation in macrophages infected with Listeria monocytogenes
K Tsuchiya, H Hara, I Kawamura, T Nomura… - The Journal of …, 2010 - journals.aai.org
Listeria monocytogenes invades the cytoplasm of macrophages and induces the activation
of caspase-1 and the subsequent maturation of IL-1β and IL-18. Although apoptosis …
of caspase-1 and the subsequent maturation of IL-1β and IL-18. Although apoptosis …