The specialized junction between a T lymphocyte and an antigen-presenting cell, the
immunological synapse, consists of a central cluster of T cell receptors surrounded by a ring …

The area of contact between a T cell and an antigen-presenting cell (APC) is known as the
immunological synapse. Although its exact function is unknown, one model suggests that it …

A central event in the development of immunity is the activation of the T cell. At the center of
this process is the T cell receptor (TCR), which triggers activation by a specific interaction …

The immunological synapse is a specialized cell-cell junction between T cell and antigen-
presenting cell surfaces. It is characterized by a central cluster of antigen receptors, a ring of …

The center of attention.(Top) The organization of the immunological synapse formed at the
interface between an antigen-presenting cell (APC) and a responding T cell. The central …

The immunological synapse is a specialized cell-cell junction that is defined by large-scale
spatial patterns of receptors and signaling molecules yet remains largely enigmatic in terms …

A synapse is a stable adhesive junction between two cells across which information is
relayed by directed secretion. The nervous system and immune system utilize these …

The contact site between T cells and antigen-presenting cells or T cells and their targets—
the immunological synapse—is a highly specialized structure potentially involved in T-cell …

The immunological synapse has been an area of very active scientific interest over the last
decade. Surprisingly, much about the synapse remains unknown or is controversial. Here …

Antigen-specific activation of T lymphocytes requires the interaction of their clonally
distributed T-cell receptors with plasma membrane ligands composed of foreign peptide …