[HTML][HTML] AG protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior

BC Lear, CE Merrill, JM Lin, A Schroeder, L Zhang… - Neuron, 2005 - cell.com
Summary The neuropeptide Pigment-Dispersing Factor (PDF) plays a critical role in
mediating circadian control of behavior in Drosophila. Here we identify mutants (groom-of …

Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF

S Hyun, Y Lee, ST Hong, S Bang, D Paik, J Kang… - Neuron, 2005 - cell.com
The pigment-dispersing factor (PDF) is a neuropeptide controlling circadian behavioral
rhythms in Drosophila, but its receptor is not yet known. From a large-scale temperature …

PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors

I Mertens, A Vandingenen, EC Johnson, OT Shafer… - Neuron, 2005 - cell.com
Summary The neuropeptide Pigment-Dispersing Factor (PDF) is a principle transmitter
regulating circadian locomotor rhythms in Drosophila. We have identified a Class II (secretin …

The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock

T Yoshii, C Wülbeck, H Sehadova, S Veleri… - Journal of …, 2009 - Soc Neuroscience
The neuropeptide pigment-dispersing factor (PDF) is a key transmitter in the circadian clock
of Drosophila melanogaster. PDF is necessary for robust activity rhythms and is thought to …

The Circadian Neuropeptide PDF Signals Preferentially through a Specific Adenylate Cyclase Isoform AC3 in M Pacemakers of Drosophila

LB Duvall, PH Taghert - PLoS biology, 2012 - journals.plos.org
The neuropeptide Pigment Dispersing Factor (PDF) is essential for normal circadian function
in Drosophila. It synchronizes the phases of M pacemakers, while in E pacemakers it …

RNA-Interference Knockdown of Drosophila Pigment Dispersing Factor in Neuronal Subsets: The Anatomical Basis of a Neuropeptide's Circadian Functions

OT Shafer, PH Taghert - PloS one, 2009 - journals.plos.org
Background In animals, neuropeptide signaling is an important component of circadian
timekeeping. The neuropeptide pigment dispersing factor (PDF) is required for several …

Ectopic expression of the neuropeptide pigment-dispersing factor alters behavioral rhythms in Drosophila melanogaster

C Helfrich-Förster, M Täuber, JH Park… - Journal of …, 2000 - Soc Neuroscience
To study the function of the neuropeptide pigment-dispersing factor (PDF) in the circadian
system of Drosophila, we misexpressed the pdf gene from the grasshopper Romalea in the …

The neuropeptide PDF acts directly on evening pacemaker neurons to regulate multiple features of circadian behavior

BC Lear, L Zhang, R Allada - PLoS biology, 2009 - journals.plos.org
Discrete clusters of circadian clock neurons temporally organize daily behaviors such as
sleep and wake. In Drosophila, a network of just 150 neurons drives two peaks of timed …

[HTML][HTML] Autoreceptor control of peptide/neurotransmitter corelease from PDF neurons determines allocation of circadian activity in Drosophila

C Choi, G Cao, AK Tanenhaus, E McCarthy, M Jung… - Cell Reports, 2012 - cell.com
Drosophila melanogaster flies concentrate behavioral activity around dawn and dusk. This
organization of daily activity is controlled by central circadian clock neurons, including the …

The neuropeptide pigment-dispersing factor coordinates pacemaker interactions in the Drosophila circadian system

Y Lin, GD Stormo, PH Taghert - Journal of Neuroscience, 2004 - Soc Neuroscience
In Drosophila, the neuropeptide pigment-dispersing factor (PDF) is required to maintain
behavioral rhythms under constant conditions. To understand how PDF exerts its influence …