Following severe injury, not just the skin but also the subcutis may be destroyed.
Consequently, the developing scar can become adherent to underlying structures …

Background: Nowadays, patients normally survive severe traumas such as burn injuries and
necrotizing fasciitis. Large skin defects can be closed but the scars remain. Scars may …

Background: Autologous fat transfer—also referred to as fat grafting—has been reported to
provide beneficial effects to overlying scar and skin. Despite procedural frequency, there is a …

Negenborn and colleagues have recently published in Plastic and Reconstructive Surgery a
very interesting systematic review based on the available published literature entitled “The …

Background: Scar tissue can cause cosmetic impairments, functional limitations, pain, and
itch. It may also cause emotional, social, and behavioral problems, especially when it is …

Materials and Methods All patients recruited had retractile and painful scars compromising
the normal daily activity/mobility of the joint involved. We performed surgical procedure with …

Background Scarring is the product of natural restoration, yet its treatment remains
challenging. Both collagen and fibroblasts are abnormally abundant in scars, leading to scar …

Background Despite civilization and progress, burns occur frequently in the world.
Remarkable discoveries of wound healing mechanisms have been reported. On the other …

Background Once an early-stage immature scar develops into a hypertrophic scar, it is
difficult to achieve satisfactory improvement with existing treatments. Therefore, the …

Background In the last decades, autologous fat grafting has been used to treat adherent
dermal scars. The observed regenerative and scar-reducing properties have been mainly …