Updated characterization of poliovirus transmission in Pakistan and Afghanistan and the impacts of different outbreak response vaccine options

DA Kalkowska, MA Pallansch, SL Cochi… - The Journal of …, 2021 - academic.oup.com
Abstract Background Pakistan and Afghanistan remain the only reservoirs of wild poliovirus
transmission. Prior modeling suggested that before the coronavirus disease 2019 (COVID …

Increasing healthy life expectancy equitably in England by 5 years by 2035: could it be achieved?

TM Marteau, M White, H Rutter, M Petticrew, OT Mytton… - The Lancet, 2019 - thelancet.com
9 Global Polio Eradication Initiative. Polio eradication & endgame strategic plan 2013–
2018.(WHO/POLIO/13.02). Geneva: World Health Organization, 2013. 10 Okayasu H, Sein …

[PDF][PDF] Circulating vaccine-derived polioviruses: current state of knowledge

OM Kew, PF Wright, VI Agol… - Bulletin of the World …, 2004 - SciELO Public Health
Within the past 4 years, poliomyelitis outbreaks associated with circulating vaccine-derived
polioviruses (cVDPVs) have occurred in Hispaniola (2000-01), the Philippines (2001), and …

Characterization of outbreak response strategies and potential vaccine stockpile needs for the polio endgame

RJ Duintjer Tebbens, MA Pallansch… - BMC Infectious …, 2016 - Springer
Background Following successful eradication of wild polioviruses and planned globally-
coordinated cessation of oral poliovirus vaccine (OPV), national and global health leaders …

Vaccine-induced mucosal immunity to poliovirus: analysis of cohorts from an open-label, randomised controlled trial in Latin American infants

PF Wright, RI Connor, WF Wieland-Alter… - The Lancet infectious …, 2016 - thelancet.com
Background Identification of mechanisms that limit poliovirus replication is crucial for
informing decisions aimed at global polio eradication. Studies of mucosal immunity induced …

Community transmission of type 2 poliovirus after cessation of trivalent oral polio vaccine in Bangladesh: an open-label cluster-randomised trial and modelling study

M Taniuchi, M Famulare, K Zaman… - The Lancet Infectious …, 2017 - thelancet.com
Background Trivalent oral polio vaccine (tOPV) was replaced worldwide from April, 2016, by
bivalent types 1 and 3 oral polio vaccine (bOPV) and one dose of inactivated polio vaccine …

The safety and immunogenicity of two novel live attenuated monovalent (serotype 2) oral poliovirus vaccines in healthy adults: a double-blind, single-centre phase 1 …

P Van Damme, I De Coster, AS Bandyopadhyay… - The Lancet, 2019 - thelancet.com
Background Use of oral live-attenuated polio vaccines (OPV), and injected inactivated polio
vaccines (IPV) has almost achieved global eradication of wild polio viruses. To address the …

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy adults: two …

I De Coster, I Leroux-Roels, AS Bandyopadhyay… - The Lancet, 2021 - thelancet.com
Background Two novel type 2 oral poliovirus vaccine (OPV2) candidates, novel OPV2-c1
and novel OPV2-c2, designed to be more genetically stable than the licensed Sabin …

[HTML][HTML] Vaccine derived poliovirus (VDPV)

A Mohanty, R Rohilla, K Zaman, V Hada… - Le Infezioni in …, 2023 - ncbi.nlm.nih.gov
Poliomyelitis is caused by Poliovirus, a member of a large group of enteroviruses. Vaccine-
derived polioviruses (VDPVs) stem from mutated live poliovirus, which is contained in the …

[HTML][HTML] Progress toward poliomyelitis eradication—Pakistan, January 2020–July 2021

C Mbaeyi - MMWR. Morbidity and Mortality Weekly Report, 2021 - cdc.gov
WPV1 cases in Pakistan declined by 43% from 2019 to 2020, and only one case has been
reported to date in 2021. A circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreak …