The epidemic and experimental studies have confirmed that the obesity can lead to
neuroinflammation, neurodegenerative diseases and adversely affect cognition. Despite the …

Diabetes mellitus can cause dysfunction of the central nervous system called “diabetic
encephalopathy”. Although various oral drugs are used to treat diabetes, they do not prevent …

Background/objectives The aim of the current study was to investigate the inhibitory effect of
lycopene (LYC), a major carotenoid present in tomato, on high-fat and high-fructose western …

Luteolin and l-theanine have anti-inflammatory, antioxidant, and possible antidiabetic
activities, and they may synergistically protect against dementia. Here, we hypothesized that …

Obesity is a multi‐factorial metabolic syndrome that increases the risk of cardiovascular
diseases, diabetes, and cancer. We recently demonstrated the antiadipogenic efficacy of …

Luteolin is a widely distributed flavone herbs and vegetables. It has anti‐oxidant and anti‐
inflammatory activities and improves glucose metabolism by potentiating insulin sensitivity …

Obesity and the brain are linked since the brain can control the weight of the body through
its neurotransmitters. The aim of the present study was to investigate the effect of high-fat …

A dysregulated overexpression of inflammatory mediators by microglia may facilitate
cognitive aging and neurodegeneration. Considerable evidence suggests the flavonoid …

Scope Although sarcopenia is mainly caused by aging, sarcopenia due to obesity has
become an emerging issue given the increase in obesity among people of various ages …

A Western diet, high in saturated fats, has been linked to the development of cognitive
impairment. Lycopene has recently received considerable attention for its potent protective …