Chronic cerebral hypoperfusion, a mild ischemic condition, is associated with the cognitive
deficits of Alzheimer's disease (AD). Luteolin, a polyphenolic compound found in foods of …

Luteolin is a flavonoid in a variety of fruits, vegetables, and herbs, which has shown anti-
inflammatory, antioxidant, and anti-cancer neuroprotective activities. In this study, we …

Overweight and obesity are now considered a worldwide pandemic and a growing public
health problem with severe economic and social consequences. Adipose tissue is an organ …

High‐fat diet (HFD) consumption has been demonstrated to cause peripheral and neuronal
insulin resistance, and brain mitochondrial dysfunction in rats. Although the dipeptidyl …

The antidepressant effect of a compound formed by co-ultramicronized
palmitoylethanolamide (PEA) and luteolin (PEA+ luteolin) was investigated in a mouse …

Obesity is one of the worldwide prevalent disease caused by the imbalance between food
intake and energy expenditure. Over a 100 years of research demonstrate that …

Obesity, caused by a high-fat diet (HFD), leads to insulin resistance, which is a precursor of
diabetes and a risk factor for impaired cognitive function, dementia, and brain diseases …

Obesity is a potential risk factor for cognitive deficits in the elder humans. Using a high‐fat
diet (HFD)–induced obese mouse model, we investigated the impacts of HFD on obesity …

It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

Diabetic encephalopathy is clinically characterized by acquired behavior and cognitive
dysfunction but its pathogenesis is not clear. This study aimed to explore the pathogenesis …