It has been well recognized that intake of diets rich in saturated fats could result in
development of metabolic disorders such as type 2 diabetes mellitus, obesity and …

Aims/hypothesis Inflammatory polarisation of adipose tissue macrophages (ATMs) plays a
critical role in the development of obesity-associated metabolic diseases such as insulin …

Cognitive dysfunction is linked to chronic low-grade inflammatory stress that contributes to
cell-mediated immunity in creating an oxidative environment. Food is a vitally important …

Altered cholesterol metabolism is believed to play a causal role in major pathophysiological
changes in neurodegeneration. Several studies have demonstrated that the absence of …

Rationale Alcoholism and obesity impart a deleterious impact on human health and affects
the quality of life. Chronic consumption of alcohol and western diet has been reported to …

Memory impairment induced by streptozotocin in rats is a consequence of changes in CNS
that are secondary to chronic hyperglycemia, impaired oxidative stress, cholinergic …

Obesity prevalence is increasing at an unprecedented rate throughout the world, and is a
strong risk factor for metabolic, cardiovascular, and neurological/neurodegenerative …

Background Obesity exerts negative effects on brain health, including decreased
neurogenesis, impaired learning and memory, and increased risk for Alzheimer's disease …

Recent findings suggest that neurotoxicity is the mechanism underlying the induction of
neuronal insulin resistance by a high cholesterol diet. Troxerutin, a naturally occurring …

The excessive intake of a high-fat diet (HFD) leads to obesity, including metabolic
syndromes, disturbs gut microbiota composition, causes colitis, and increases the plasma …