The effects of continuous and intermittent reduced speed modes on renal and intestinal perfusion in an ovine model

E Tuzun, K Chorpenning, MQ Liu, K Bonugli… - ASAIO …, 2014 - journals.lww.com
The effects of the continuous-flow output on renal and intestinal microcirculation have not
been extensively studied. To address this, the Heartware HVAD pump loaded with …

Measurement of hemodynamic energy at different vessels in an adult swine model

KH Son, CB Ahn, SH Lee, HS Son, J Choi… - ASAIO …, 2010 - journals.lww.com
Extra hemodynamic energy is one of the major benefits of pulsatile flow, improving blood
flow to vital organs. But most (80%) of the hemodynamic energy generated from pulsatile …

Controller for an axial flow blood pump

H Konishi, JF Antaki, DV Amin, JR Boston… - Artificial …, 1996 - Wiley Online Library
A rotary blood pump inherently provides only one noninvasive “observable '” parameter
(motor current) and allows for only one “controllable” parameter (pump speed). To maintain …

Total heart replacement using dual intracorporeal continuous-flow pumps in a chronic bovine model: a feasibility study

OH Frazier, E Tuzun, WE Cohn, JL Conger… - ASAIO …, 2006 - journals.lww.com
Continuous-flow pumps are small, simple, and respond physiologically to input variations,
making them potentially ideal for total heart replacement. However, the physiological effects …

Rotary pump speed modulation for generating pulsatile flow and phasic left ventricular volume unloading in a bovine model of chronic ischemic heart failure

KG Soucy, GA Giridharan, Y Choi, MA Sobieski… - The Journal of Heart and …, 2015 - Elsevier
Background Rotary blood pumps operate at a constant speed (rpm) that diminishes vascular
pulsatility and variation in ventricular end-systolic and end-diastolic volumes, which may …

Afterload‐Dependent Flow Fluctuation of Centrifugal Pump: Should it be Actively Fixed?

H Nishida, T Akazawa, T Nishinaka, S Aomi… - Artificial …, 1998 - Wiley Online Library
To evaluate the clinical meaning and effects of afterload‐dependent flow fluctuation in a
centrifugal pump, concomitant measurement of flow rate and mixed venous oxygen …

Rotary blood pump flow spontaneously increases during exercise under constant pump speed: results of a chronic study

T Akimoto, K Yamazaki, P Litwak, KN Litwak… - Artificial …, 1999 - Wiley Online Library
Many types of rotary blood pumps and pump control methods have recently been developed
with the goal of clinical use. From experiments, we know that pump flow spontaneously …

Dynamic systemic vascular resistance in a sheep supported with a Nimbus AxiPump

H Konishi, JF Antaki, JR Boston, JP Kerrigan… - ASAIO …, 1994 - journals.lww.com
Abstract Changes in systemic vascular resistance (SVR) in response to diminished pulse
perfusion were analyzed over a dynamic range of flow conditions. An axial flow LVAD …

Continuous-flow pump model study: the effect on pump performance of pump characteristics and cardiovascular conditions

G Ferrari, M Kozarski, L Fresiello, AD Molfetta… - Journal of Artificial …, 2013 - Springer
This model study evaluates the effect of pump characteristics and cardiovascular data on
hemodynamics in atrio–aortic VAD assistance. The model includes a computational …

Hemodynamic characteristics of a mixed flow pump prototype: progress report of in vitro and acute animal experiments

M Carrier, MI Farinas, A Garon - ASAIO journal, 2006 - journals.lww.com
A new dual-inlet mixed-flow blood pump was designed and tested in our laboratory. The
objective of the present study was to analyze hemodynamic characteristics of the pump …