The complexity of the human brain emerges from a long and finely tuned developmental
process orchestrated by the crosstalk between genome and environment. Vis à vis other …

Neurodevelopmental disorders (NDDs), including intellectual disability (ID) and autism
spectrum disorders (ASD), are a large group of disorders in which early insults during brain …

Chromatin-related genes are frequently mutated in neurodevelopmental disorders; yet, the
mechanisms by which these perturbations disrupt brain assembly and function are not …

Disruption of chromatin structure due to epimutations is a leading genetic etiology of
neurodevelopmental disorders, collectively known as chromatinopathies. We show that …

The brain comprises many different cell types with specialized functions which respond and
adapt to the continuously changing environment, through tight spatiotemporal regulation of …

The diverse number of neurons in the cerebral cortex are generated during development by
neural stem cells lining the ventricle, and they continue maturing postnatally. Dynamic …

Epigenetics is the array of the chromatin modifications that customize in cell-, stage-, or
condition-specific manner the information encloses in plain DNA molecules. Increasing …

Postmitotic neurons are subject to a vast array of environmental influences that require the
nuclear integration of intracellular signaling events to promote a wide variety of neuroplastic …

Neurodevelopmental diseases (NDDs), such as autism spectrum disorders, epilepsy, and
schizophrenia, are characterized by diverse facets of neurological and psychiatric …

Aberrant changes in gene function are believed to be involved in a wide spectrum of human
disease including behavioral, cognitive and neurodegenerative pathologies. Most of the …