Critical intracellular Ca2+ dependence of transient receptor potential melastatin 2 (TRPM2) cation channel activation

D McHugh, R Flemming, SZ Xu, AL Perraud… - Journal of Biological …, 2003 - ASBMB
TRPM2 is a member of the melastatin-related TRP (transient receptor potential) subfamily. It
is expressed in brain and lymphocytes and forms a cation channel that is activated by …

Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel

B Tóth, L Csanády - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …

Intracellular calcium activates TRPM2 and its alternative spliced isoforms

J Du, J Xie, L Yue - Proceedings of the National Academy of …, 2009 - National Acad Sciences
Melastatin-related transient receptor potential channel 2 (TRPM2) is a Ca2+-permeable,
nonselective cation channel that is involved in oxidative stress-induced cell death and …

The Ca2+‐activated cation channel TRPM4 is regulated by phosphatidylinositol 4,5‐biphosphate

B Nilius, F Mahieu, J Prenen, A Janssens… - The EMBO …, 2006 - embopress.org
Transient receptor potential (TRP) channel, melastatin subfamily (TRPM) 4 is a Ca2+‐
activated monovalent cation channel that depolarizes the plasma membrane and thereby …

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions

S Lambert, A Drews, O Rizun, TFJ Wagner, A Lis… - Journal of Biological …, 2011 - ASBMB
TRPM1 is the founding member of the melastatin subgroup of transient receptor potential
(TRP) proteins, but it has not yet been firmly established that TRPM1 proteins form ion …

Ca2+‐dependent induction of TRPM2 currents in hippocampal neurons

ME Olah, MF Jackson, H Li, Y Perez… - The Journal of …, 2009 - Wiley Online Library
TRPM2 is a Ca2+‐permeable member of the transient receptor potential melastatin family of
cation channels whose activation by reactive oxygen/nitrogen species (ROS/RNS) and ADP …

Trpm2

M Faouzi, R Penner - … Transient Receptor Potential (TRP) Cation Channels …, 2014 - Springer
TRPM2 is the second member of the transient receptor potential melastatin-related (TRPM)
family of cation channels. The protein is widely expressed including in the brain, immune …

The role of TRPM channels in cell death

S McNulty, E Fonfria - Pflügers Archiv, 2005 - Springer
Transient receptor potential (TRP) channels of the melastatin-like family (TRPM) play critical
roles in mediating cellular responses to a wide range of physiological stimuli that, under …

The mammalian melastatin-related transient receptor potential cation channels: an overview

R Kraft, C Harteneck - Pflügers Archiv, 2005 - Springer
The mammalian melastatin-related transient receptor potential (TRPM) subfamily contains
eight members. TRPM proteins, consisting of six putative transmembrane domains and …

Identification and characterization of the murine TRPM4 channel

M Murakami, F Xu, I Miyoshi, E Sato, K Ono… - … and biophysical research …, 2003 - Elsevier
The transient receptor potential (TRP) channels form a superfamily with six transmembrane
structures, which is common in other types of voltage-dependent channels. The TRP …