Possible biomarkers for cancer immunotherapy
T Otoshi, T Nagano, M Tachihara, Y Nishimura - Cancers, 2019 - mdpi.com
Immune checkpoint inhibitors (ICIs) have drastically changed the clinical care of cancer.
Although cancer immunotherapy has shown promise in various types of malignancies, thus …
Although cancer immunotherapy has shown promise in various types of malignancies, thus …
[HTML][HTML] Biomarkers for predicting the efficacy of immune checkpoint inhibitors
Immune checkpoint blockade has vastly changed the landscape of cancer treatment and
showed a promising prognosis for cancer patients. However, there is still a large portion of …
showed a promising prognosis for cancer patients. However, there is still a large portion of …
'Know thyself'–host factors influencing cancer response to immune checkpoint inhibitors
A Gunjur, AJ Manrique‐Rincón, O Klein… - The Journal of …, 2022 - Wiley Online Library
Immune checkpoint inhibitors (ICIs) have revolutionised oncology and are now standard‐of‐
care for the treatment of a wide variety of solid neoplasms. However, tumour responses …
care for the treatment of a wide variety of solid neoplasms. However, tumour responses …
Biomarkers for predicting the outcome of various cancer immunotherapies
L Jafarzadeh, M Khakpoor-Koosheh, H Mirzaei… - Critical reviews in …, 2021 - Elsevier
Cancer immunotherapy has appeared as a well-known therapeutic modality for different
cancers. Yet, only a subset of patients derive clinical benefit. It is thus critical to understand …
cancers. Yet, only a subset of patients derive clinical benefit. It is thus critical to understand …
Novel biomarkers for personalized cancer immunotherapy
Y Shindo, S Hazama, R Tsunedomi, N Suzuki… - Cancers, 2019 - mdpi.com
Cancer immunotherapy has emerged as a novel and effective treatment strategy for several
types of cancer. Immune checkpoint inhibitors (ICIs) have recently demonstrated impressive …
types of cancer. Immune checkpoint inhibitors (ICIs) have recently demonstrated impressive …
Current landscape and future directions of biomarkers for predicting responses to immune checkpoint inhibitors
Y Zhu, F Zhao, Z Li, J Yu - Cancer Management and Research, 2018 - Taylor & Francis
Immune checkpoint inhibitors (ICIs), represented by anti-CTLA-4 or anti-PD-1/anti-PD-L1
pathway antibodies, have led to a revolution in cancer treatment modalities. ICIs have …
pathway antibodies, have led to a revolution in cancer treatment modalities. ICIs have …
Possibilities of improving the clinical value of immune checkpoint inhibitor therapies in cancer care by optimizing patient selection
S Iivanainen, JP Koivunen - International Journal of Molecular Sciences, 2020 - mdpi.com
Immune checkpoint inhibitor (ICI) therapies have become the most important medical
therapies in many malignancies, such as melanoma, non-small-cell lung cancer, and …
therapies in many malignancies, such as melanoma, non-small-cell lung cancer, and …
FDA-approved and emerging next generation predictive biomarkers for immune checkpoint inhibitors in cancer patients
Y Wang, Z Tong, W Zhang, W Zhang, A Buzdin… - Frontiers in …, 2021 - frontiersin.org
A patient's response to immune checkpoint inhibitors (ICIs) is a complex quantitative trait,
and determined by multiple intrinsic and extrinsic factors. Three currently FDA-approved …
and determined by multiple intrinsic and extrinsic factors. Three currently FDA-approved …
Predictive biomarkers for tumor immune checkpoint blockade
M Tong, J Wang, W He, Y Wang, H Pan… - Cancer management …, 2018 - Taylor & Francis
The development of immune checkpoint inhibitors represented by PD-1 and PD-L1 has
provided new hope for the treatment of advanced cancer patients. However, there are no …
provided new hope for the treatment of advanced cancer patients. However, there are no …
Validation of biomarkers to predict response to immunotherapy in cancer: volume II—clinical validation and regulatory considerations
KK Dobbin, A Cesano, J Alvarez, R Hawtin… - … for immunotherapy of …, 2016 - Springer
There is growing recognition that immunotherapy is likely to significantly improve health
outcomes for cancer patients in the coming years. Currently, while a subset of patients …
outcomes for cancer patients in the coming years. Currently, while a subset of patients …