Innate immune evasion by SARS‐CoV‐2: comparison with SARS‐CoV

A Bouayad - Reviews in medical virology, 2020 - Wiley Online Library
Summary SARS‐CoV‐2 virus, a member of the Coronaviridae family, causes Covid‐19
pandemic disease with severe respiratory illness. Multiple strategies enable SARS‐CoV‐2 …

The molecular mechanism of SARS-CoV-2 evading host antiviral innate immunity

W Gu, H Gan, Y Ma, L Xu, ZJ Cheng, B Li, X Zhang… - Virology journal, 2022 - Springer
Abstract The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has resulted in a global health emergency (COVID-19) because of its rapid spread …

The battle between host and SARS-CoV-2: Innate immunity and viral evasion strategies

S Zhang, L Wang, G Cheng - Molecular therapy, 2022 - cell.com
The SARS-CoV-2 virus, the pathogen causing COVID-19, has caused more than 200 million
confirmed cases, resulting in more than 4.5 million deaths worldwide by the end of August …

Characterization of SARS-CoV-2 evasion: interferon pathway and therapeutic options

M Znaidia, C Demeret, S van der Werf, AV Komarova - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. SARS-CoV-2 is characterized by an important capacity to …

SARS-CoV-2-mediated evasion strategies for antiviral interferon pathways

SJ Oh, OS Shin - Journal of Microbiology, 2022 - Springer
With global expansion of the COVID-19 pandemic and the emergence of new variants,
extensive efforts have been made to develop highly effective antiviral drugs and vaccines …

Covid-19: perspectives on innate immune evasion

N Taefehshokr, S Taefehshokr, N Hemmat… - Frontiers in …, 2020 - frontiersin.org
The ongoing outbreak of Coronavirus disease 2019 infection achieved pandemic status on
March 11, 2020. As of September 8, 2020 it has caused over 890,000 mortalities world-wide …

Innate immune response and inflammasome activation during SARS-CoV-2 infection

M Islamuddin, SA Mustfa, SNMN Ullah, U Omer, K Kato… - Inflammation, 2022 - Springer
The novel coronavirus SARS-CoV-2, responsible for the COVID-19 outbreak, has become a
pandemic threatening millions of lives worldwide. Recently, several vaccine candidates and …

Coronaviruses: innate immunity, inflammasome activation, inflammatory cell death, and cytokines

SJ Lee, R Channappanavar, TD Kanneganti - Trends in immunology, 2020 - cell.com
The innate immune system acts as the first line of defense against pathogens, including
coronaviruses (CoVs). Severe acute respiratory syndrome (SARS)-CoV and Middle East …

[HTML][HTML] Differences and similarities between innate immune evasion strategies of human coronaviruses

H Hoenigsperger, R Sivarajan, KMJ Sparrer - Current Opinion in …, 2024 - Elsevier
Highlights•Human coronaviruses use distinctand similar strategies to counteract innate
defenses.•Insights from SARS-CoV-2 will inspire research on endemic and epidemic …

Innate immune evasion strategies of SARS-CoV-2

JM Minkoff, B tenOever - Nature Reviews Microbiology, 2023 - nature.com
Abstract SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has been
associated with substantial global morbidity and mortality. Despite a tropism that is largely …