The molecular biology and novel treatments of vestibular schwannomas: a review

B Fong, G Barkhoudarian, P Pezeshkian… - Journal of …, 2011 - thejns.org
Vestibular schwannomas are histopathologically benign tumors arising from the Schwann
cell sheath surrounding the vestibular branch of cranial nerve VIII and are related to the NF2 …

Tumor biology of vestibular schwannoma: a review of experimental data on the determinants of tumor genesis and growth characteristics

M de Vries, AGL van der Mey… - Otology & …, 2015 - journals.lww.com
Objective Provide an overview of the literature on vestibular schwannoma biology with
special attention to tumor behavior and targeted therapy. Background Vestibular …

Molecular biology of familial and sporadic vestibular schwannomas: implications for novel therapeutics: A review

ME Sughrue, AH Yeung, MJ Rutkowski… - Journal of …, 2011 - thejns.org
Vestibular schwannomas (VSs) are benign tumors arising from the sheath of cranial nerve
VIII. The pathogenesis underlying most familial and sporadic VSs has been linked to a …

Molecular studies of vestibular schwannomas: a review

DB Welling, MD Packer, LS Chang - Current opinion in …, 2007 - journals.lww.com
Molecular studies of vestibular schwannomas: a review : Current Opinion in Otolaryngology &
Head and Neck Surgery Molecular studies of vestibular schwannomas: a review : Current …

The molecular biology of vestibular schwannomas: dissecting the pathogenic process at the molecular level

BA Neff, DB Welling, E Akhmametyeva… - Otology & …, 2006 - journals.lww.com
Objective: The goal of this article was to review concisely what is currently known about the
tumorigenesis of vestibular schwannomas. Background: Recent advances in molecular …

An update on the diagnosis and treatment of vestibular schwannoma

J Halliday, SA Rutherford, MG McCabe… - Expert review of …, 2018 - Taylor & Francis
Introduction: Vestibular schwannomas (VS) account for approximately 85% of tumors in the
cerebello-pontine angle, with a lifetime incidence of approximately 1 in 1000. Most are …

Genesis and biology of vestibular schwannomas

PH Roche, C Bouvier, O Chinot… - Modern management of …, 2008 - karger.com
This review chapter is a synthesis of the recent literature about pathogenesis of
schwannomas with emphasis on vestibular schwannomas (VSs). The cornerstone of cellular …

Merlin knockdown in human Schwann cells: clues to vestibular schwannoma tumorigenesis

Z Ahmad, CM Brown, AK Patel, AF Ryan… - Otology & …, 2010 - journals.lww.com
Background: Neurofibromatosis 2 (NF2)-related and sporadic vestibular schwannoma (VS)
exhibit loss of functional merlin (schwannomin). After loss of merlin expression in the …

ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy

JK Doherty, W Ongkeko, B Crawley… - Otology & …, 2008 - journals.lww.com
Objective: Identify molecular targets for development of tumor-specific
pharmacotherapeutics aimed at treating vestibular schwannomas (VSs). Activated …

A review of drug therapy in vestibular schwannoma

J Long, Y Zhang, X Huang, J Ren… - Drug Design …, 2021 - Taylor & Francis
Vestibular schwannomas (VSs, also known as acoustic neuromas) are benign intracranial
tumors commonly managed with observation, surgery, and radiotherapy. There is currently …