Renal chemerin expression is induced in models of hypertensive nephropathy and glomerulonephritis and correlates with markers of inflammation and fibrosis

A Mocker, KF Hilgers, N Cordasic, R Wachtveitl… - International journal of …, 2019 - mdpi.com
Chemerin and its receptor, chemokine-like receptor 1 (CmklR1), are associated with
chemotaxis, inflammation, and endothelial function, especially in metabolic syndrome …

Chemerin levels in chronic kidney disease: A systematic review and meta-analysis

AH Behnoush, P Shobeiri, P Bahiraie… - Frontiers in …, 2023 - frontiersin.org
Introduction Chemerin as an inflammatory biomarker has gained attention in its biomarker
capability. Several studies measured its levels in chronic kidney disease (CKD), as one of …

Chemerin in renal dysfunction and cardiovascular disease

M Bonomini, A Pandolfi - Vascular pharmacology, 2016 - Elsevier
The potential involvement of chemerin in cardiovascular and renal dysfunction has recently
been acknowledged. There are indeed many links between this protein and inflammation …

Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy

J Shang, L Wang, Y Zhang, S Zhang… - Journal of cellular …, 2019 - Wiley Online Library
Diabetic nephropathy (DN) is characterized by inflammation of renal tissue. Glomerular
endothelial cells (GEnCs) play an important role in inflammation and protein leakage in …

Serum chemerin levels are inversely associated with renal function in a general population

S Zylla, R Rettig, H Völzke, K Endlich… - Clinical …, 2018 - Wiley Online Library
Objective Chemerin has been found to be highly expressed in the kidneys of rodents and
has been suggested to affect metabolic syndrome (MetS)‐related phenotypes which are in …

Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR 1), not G‐Protein‐Coupled Receptor 1 (GPR 1), in Human and Rat Vasculature

AJ Kennedy, P Yang, C Read, RE Kuc… - Journal of the …, 2016 - Am Heart Assoc
Background Circulating levels of chemerin are significantly higher in hypertensive patients
and positively correlate with blood pressure. Chemerin activates chemokine‐like receptor 1 …

Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis

J Kaur, R Adya, BK Tan, J Chen… - … and biophysical research …, 2010 - Elsevier
Chemerin acting via its distinct G protein-coupled receptor CMKLR1 (ChemR23), is a novel
adipokine, circulating levels of which are raised in inflammatory states. Chemerin shows …

Rosiglitazone ameliorates diabetic nephropathy by reducing the expression of Chemerin and ChemR23 in the kidney of streptozotocin-induced diabetic rats

W Hu, Q Yu, J Zhang, D Liu - Inflammation, 2012 - Springer
Chemerin is shown to be associated with inflammation which is involved in the
pathogenesis of diabetic nephropathy. This study aims to determine whether rosiglitazone …

Chemerin in inflammatory diseases

X Su, Y Cheng, G Zhang, B Wang - Clinica Chimica Acta, 2021 - Elsevier
Obesity is associated with a series of health problems. Adipocytes are a huge repository of
energy as well as an important source of many adipokines. In obesity, adipocytes are …

Chemerin inhibits vascular calcification through ChemR23 and is associated with lower coronary calcium in chronic kidney disease

M Carracedo, A Witasp, AR Qureshi… - Journal of Internal …, 2019 - Wiley Online Library
Background Chemerin is an adipokine that signals through the G protein‐coupled receptor
ChemR23 and is associated with inflammation, glucose homeostasis, lipid metabolism and …