Acetylcholine (ACh) is an important neurotransmitter of the CNS that binds both nicotinic and
muscarinic receptors to exert its action. However, the mechanisms underlying the effects of …

Wide innervation of cholinergic projections throughout the cortex implies that acetylcholine
(ACh) plays an essential role in information processing, but how it works is still enigmatic …

The critical role of acetylcholine (ACh) in the basal ganglia is evident from the effect of
cholinergic agents in patients suffering from several related neurological disorders, such as …

The neurotransmitter acetylcholine (ACh) can regulate neuronal excitability throughout the
nervous system by acting on both the cys-loop ligand-gated nicotinic ACh receptor channels …

Cholinergic inputs from the basal forebrain to the neocortex and hippocampus have a key
role in mechanisms of arousal, attention, sensory processing, and memory. Acetylcholine …

Extensive physiological research has demonstrated a number of common effects of
acetylcholine within cortical structures, including the hippocampus, piriform cortex, and …

Research on the nicotinic cholinergic system function in the brain was previously mainly
derived from animal studies, yet, research in humans is growing. Up to date, findings allow …

Acetylcholine (ACh) is believed to act as a neuromodulator in cortical circuits that support
cognition, specifically in processes including learning, memory consolidation, vigilance …

Acetylcholine (ACh) signaling shapes neuronal circuit development and underlies specific
aspects of cognitive functions and behaviors, including attention, learning, memory and …

Cholinergic afferents from the basal forebrain (BF) can influence cortical activity on rapid
time scales, enabling sensory information processing and exploratory behavior. However …